Measurement solutions for modern drugs
This edition is less about excipients but a very important topic within the pharma and biotech industry. The substances we handle are becoming more and more complex but the measurement seem not always keep up with the pace as for example in chiral analytics. Therefore I would like to present you the solutions from ENANTIOS which is a potential game changer in chiral analytics.
Addressing the measurement gap in pharma:
Despite decades of advancement and rapid changes in pharmaceutical drugs, the methods used to characterize drugs during development and manufacturing have largely remained the same This “measurement gap” represents a significant barrier to drug development and manufacturing. At ENANTIOS, we leverage advances in measurement technology to address this gap. We have developed a new analytical tool for the characterization of complex pharmaceutical molecules. Our technology allows customers to quickly screen large numbers of molecules early in the development process, and test quality more easily in manufacturing for modern, structurally complex drugs. This lowers the cost of new drug development and enables more accurate testing in manufacturing.
MEASUREMENT SOLUTIONS FOR MODERN DRUGS
Understanding molecular structure is a key step in understanding how a molecule will interact with the body. Despite advances in modern pharmaceutical molecules, the tools used for characterization have largely remained the same. This slows down drug discovery and increases costs in manufacturing.
We leverage advances in measurement technology to enable our users to determine the structure of complex chiral molecules and biologics.
Current technology vs. our technology measuring modern drugs:
The Technology
Enantios′ technology is based on an optical effect known as Raman Optical Activity (ROA).
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This effect can determine the structure of complex chiral molecules and biologics, can be measured on almost all molecule types, and can be measured in a variety of solvents, including aqueous (biologically relevant) buffer solutions. Unlike currently used techniques, ours can be used without calibration on virtually any molecule and can be used without a second analytical technique.
A comparison of the use of our technology (ROA) vs the current technology:
Interested to learn more? Get in touch with Enantios here
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