Longevity: Paradise
Donna Kawasaki, PhD, EMBA, MBA
Top 5% Global Fortune1000 CEO, CMO, CTO, COO, SVP | Top 100 World-Wide for Innovative Solutions | AI | E-Commerce | Brand Champion | Quality Improvement | Musician | Athlete | Mother
Longevity is relevant to every other industry. It provides continuity and with this high value relationships, and a happier and more productive team. The highest value technology to benefit humanity and create wealth.
9 Areas of Longevity: Paradise
Epigenetic Reprogramming
Hold on to your hats, folks! We're diving into one of the most sizzling hot areas in longevity research. It's so hot, it makes the sun look like a night light.
What is it? Imagine your DNA as a massive cookbook filled with billions of recipes handed down from your parents. Now, some recipes are in constant use while others gather dust on the shelf. Your epigenome is the chef that decides which recipes (genes) to cook up and which to leave in the book. Epigenetic reprogramming is like convincing the chef to revisit those old favorites from your youth to keep you feeling spry.
Here are three of the culinary geniuses leading the charge:
Altos Labs (Backed by Jeff Bezos and Yuri Milner, and led by CEO Hal Barron, MD) is flipping the aging process on its head. With $3 billion in funding and four Nobel laureates on their team, they’re cooking up medicines to rejuvenate cells, making them as healthy and resilient as a teenager’s skin at a TikTok convention.
NewLimit (Co-founded by Coinbase CEO Brian Armstrong and Blake Byers, PhD) is all about epigenetic reprogramming to restore T cell and liver function. Think of them as the master chefs preparing the body’s immune system and liver for a renaissance feast.
Retro Bio (Backed by OpenAI CEO Sam Altman and led by CEO Joe Betts-LaCroix) is using cutting-edge automation and computational biology to add a decade or more to your life. They’re developing five-star treatments to reverse cellular aging and even offer "micro replacement" therapies for that extra youthful zest.
Stem Cell / Cellular Medicine
Stem cells are like the body’s Swiss Army knife. They can transform into heart cells, neurons, liver cells, and more. But as we age, our stem cell toolkit gets a bit rusty. These companies are polishing those tools to make us as good as new.
Celularity by Dr. Bob Hariri is using stem cells derived from the placenta to revolutionize longevity. It's like getting a brand new toolkit straight from the factory.
Immunis (Co-founded by Hans Keirstead, PhD) is addressing age-related muscle loss with cutting-edge stem cell secretome technology. Their approach is akin to giving your muscles a VIP backstage pass to the fountain of youth.
CRISPR / Gene Therapy
Gene therapy is like having a magic wand for your DNA, allowing us to edit genes or insert new ones to fix what’s broken.
Gordian Biotechnology (Co-founded by Martin Borch Jensen and Francisco LePort, PhD) is cracking the code on genetic research with the finesse of a maestro conducting a symphony.
Rejuvenate Bio (Founded by Harvard's Dr. George Church and led by Daniel Oliver, MBA) is using CRISPR to introduce longevity gene combinations. They’re not just slowing aging—they’re flipping it into reverse like a high-speed car chase in a blockbuster movie.
AI Drug Development
AI is like having a super-intelligent chef who can whip up new drugs overnight. These companies are setting the table with an endless buffet of novel therapeutics.
Fauna Bio (Co-founded by Ashley Zehnder) is analyzing 452 animal species to uncover obesity treatments. They’ve partnered with Eli Lilly to make sure no one’s left hungry.
Rubedo Life Sciences (Co-founded by Marco Quarta, PhD) is using AI and single-cell RNA sequencing to cook up new therapies for psoriasis and scleroderma, aiming to keep you vibrant at any age.
Verge Genomics (Founded by Alice Zhang) is using its CONVERGE? technology to tackle neurodegenerative diseases like ALS, ensuring your brain and body stay in top form.
领英推荐
BioAge Labs (Co-founded by Kristen Fortney, PhD) is leveraging AI to discover drugs for aging and metabolic diseases. They’ve created Azelaprag, an oral drug for weight loss and metabolic health, which might just be the dietary supplement of the future.
Phenome Health (Led by Lee Hood, MD, PhD and James Yurkovich, PhD) is combining multi-omics, AI, and big data to combat aging. Their holistic approach could make personalized health as common as a cup of coffee.
Neurocognitive Rejuvenation
Moving beyond the social media buzz, these companies are tackling the heavy hitters like Alzheimer’s and Parkinson’s, aiming to keep your brain sharp and your wit even sharper.
Science, founded by Max Hodak, is developing brain-computer interfaces and working to cure blindness. Their Science Eye combines gene therapy with implanted micro-LED displays to restore vision. Imagine seeing the world with the clarity of a hawk and the intellect of a scholar.
Vaxxinity, led by Lou Reese, is developing immunotherapies that cross the blood-brain barrier to address Parkinson’s and Alzheimer’s. Picture getting a brain upgrade with just a couple of shots per year.
Cancer Diagnostics & Therapeutics
Early detection is key, and these companies are leading the charge in spotting cancer before it has a chance to spread.
ExThera Medical (Led by Lakhmir Chawla, MD) is revolutionizing blood filtration to remove harmful substances from the bloodstream, including cancer cells. It's like having a personal bodyguard for your blood.
Metabolic / Inflammatory
From high blood pressure to diabetes, these companies are tackling the metabolic issues that plague so many.
Biolinq, led by CEO Rich Yang, is developing a wearable patch that continuously monitors multiple biomarkers without causing discomfort. It’s like having a mini medical lab attached to your skin, giving you real-time health insights.
Diagnostic & Imaging
Advanced diagnostics and imaging technologies are making it easier to catch diseases early, ensuring that treatments are more effective.
Q.Bio , led by Jeff Kaditz, Clarissa Shen, and Dr. Michael Snyder, offers a 10-minute full-body MRI scan. Say goodbye to claustrophobic panic attacks and hello to early disease detection.
Microbiome
Your body is home to trillions of bacteria and microbes that play a crucial role in your overall health.
Susan Lynch, Director of The Benioff Center for Microbiome Medicine at UCSF, is leading research into how these microbial communities impact conditions like asthma, obesity, and inflammatory diseases. It’s like having a personal ecosystem that keeps you healthy.
Why This Matters
How long do you think you’ll live? What if we could add an additional ten, twenty, thirty healthy years to your life? Imagine a future where no one dies from cancer, Alzheimer’s, heart disease, or any other disease of aging because we've learned to prevent them with next-generation diagnostics or vaccines. For the first time in history, billions of dollars and thousands of brilliant minds are committed to extending the human healthspan, ensuring we live longer, healthier lives.
Additional Leaders in Longevity
Get ready for a future where living to 100 is just the beginning and feeling 30 at 70 is the new normal. The longevity revolution is here, and it’s not just about adding years to your life, but life to your years.