Lab Notes Newsletter
Welcome to the February edition of our newsletter!
For 40 years, we’ve helped scientists harness the full potential of biology with next-generation technology. Here we share the latest in automated, end-to-end solutions that span research disciplines to advance scientific discovery and improve the quality of human life worldwide.
Introducing the NEW ImageXpress HCS .ai High-Content Screening System?
Say hello to the newest addition to our industry-leading high-content imaging portfolio.??
? Versatile and easy-to-use
The ImageXpress? HCS .ai system features a modular design, a wide array of configuration options, and intuitive acquisition software, enabling you to easily meet both current and future needs.
? High-quality images and superior data analysis for deeper insights
Get high-quality images across a vast range of assay types, acquire exceptional image quality from your 3D samples, and unlock new discoveries with AI-powered IN Carta? Image Analysis Software.?
? Fast acquisition for accelerated high-throughput workflows
Boost lab productivity by imaging more plates in less time, getting new users started faster than ever before, and easily integrating the system into automated workflows.
FEATURE ARTICLE: 2025 Trends: Organoids?
In this perspective piece from Genetic Engineering & Biotechnology News, leading R&D experts share their perspectives on where the organoid market is headed in the coming years. Among them, Molecular Devices President Mary Duseau highlights the rapid adoption of organoids in research, with nearly 40% of scientists already using them—a number expected to double by 2028.?
However, challenges like reproducibility and batch variability remain. To address these, Duseau emphasizes how automation and AI are driving standardization, improving consistency, and reducing human bias. By leveraging these technologies, researchers can develop assay-ready organoid models that accelerate drug discovery and disease research.
Advancing Organoid Research with Microplate Readers
Discover how our SpectraMax Microplate Readers streamline drug discovery in organoid research. From assessing colorectal cancer organoid viability to evaluating drug effects with a walkaway solution, these resources showcase automated, high-throughput solutions for accelerating breakthroughs in precision medicine:
ON-DEMAND WEBINAR: Accelerating Cancer Research: Microplate reader-based viability analysis for rapid drug candidate identification in patient-derived organoids
Dive into organoid-based cancer research and discover how microplate readers can transform your drug discovery process. This webinar, presented by Dr. Krystal Belmonte and Dr. Angeline Lim, showcases innovative techniques for identifying and assessing drug candidates using patient-derived colorectal cancer organoids. Learn how to leverage microplate reader technology to streamline and enhance your research.
APPLICATION NOTE: Rapid walkaway solution for assessing viability in patient-derived colorectal cancer organoids
In this application note, we demonstrate the utility of label-free imaging and an ATP-based viability assay for rapidly gauging drug responses, with automation of liquid handling and microplate transport to decrease hands-on time. This streamlined readout may be used to guide identification of potential therapeutics earlier in the screening process, which can then be followed up with more intensive high content imaging or other analyses.
APPLICATION NOTE: Functional analysis of spontaneous calcium oscillations of iPSC-derived 3D neural organoids?
Induced pluripotent stem cell (iPSC)-derived neural organoids are a rapidly evolving technology with the potential to better understand brain development, disease, and disorders within the context of diverse genetic backgrounds.
In this new application note, we focus on the functional characterization of spontaneous activity in neural organoids as measured by calcium oscillations. In addition, by automating key processes, we were able to reduce manual labor while maintaining optimal culture conditions to ensure consistent monitoring of organoid development and activity and enable efficient high-throughput screening of compounds.
EVENTS?
March 16-20, 2025 | Orlando, FL?
April 25-30, 2025 | Chicago, IL?
May 05-08, 2025 | San Jose, CA