Innovation in Protein and DNA Design
In 2022, a major breakthrough occurred: For the first time, protein-based therapeutics reached half of all new FDA-approved drugs in the US. Driven by revolutionary AI-powered #proteindesign, antibodies, and therapeutic proteins have now taken the spotlight in drug development.
Today, I introduce you to Gigabases, a free-access platform empowering scientists with AI to effortlessly craft 3D protein designs and custom DNA orders, catalyzing a new era of biotechnological innovation.
3D Protein Structure Prediction
Recently, the combination of 3D protein design and AI has felt like a futuristic idea. However, DeepMind’s AlphaFold has changed that by predicting millions of proteins across all domains of life. This renowned AI model has decoded how amino acids fold into 3D structures, providing valuable insights into protein functions and potential drug targets.
From Computer Models to Cellular Reality
A Swiss startup called Gigabases, which is a spin-off from #ethzurich, has successfully merged AI-based protein structure prediction with digital DNA design.
Gigabases can convert 3D protein models into DNA and then produce and distribute the corresponding DNA to scientists around the world. Researchers can then use this DNA to direct cells to create therapeutic protein prototypes that have been developed using computer algorithms.
Access a Vast Protein Selection: Using Gigabases’ Platform, you have access to over 214 million proteins that cater to diverse #biotechnology and research requirements.
Design Protein Prototypes: The platform's user-friendly digital tools simplify protein engineering, enabling the modification of individual amino acids.
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Customize DNA Plasmids: Additionally, through beta access, the platform offers customized DNA plasmids to researchers worldwide. You can easily find, customize, and order proteins as DNA plasmids on Gigabases’ platform without requiring DNA design skills, thanks to the platform’s algorithms.
Impacting Biotechnology and Beyond
AI technology has the potential to revolutionize drug discovery, enzyme engineering, and #biotherapeutics beyond the confines of the laboratory. Imagine a future where custom-designed proteins can precisely combat diseases and enzymes optimize sustainable industrial processes.
Embracing the Opportunity
As professionals committed to advancing science and innovation, we are presented with an exciting opportunity to explore new approaches in protein and DNA design with the help of AI innovation. This will drive advancements that were once thought of as futuristic.
I invite you to explore Gigabases, engage in scientific discourse, and contribute to the exciting evolution of AI-driven protein and DNA design.
#dnadesign #pharmaceuticals Gigabases Switzerland AG
Stanislav Pantelyushin Chandramouli Chillakuri Simone Fulle
Giovanni Magistrelli
Mathilde Testut
Alexander Rau