The importance of particle size distribution (PSD) in the milling process

Achieving an ideal PSD guarantees that particles maintain consistent behavior during critical processes like dissolution and formulation. PSD analysis is paramount in the production of medications, where particle size consistency is vital for the bioavailability of the active ingredient, thereby directly influencing the treatment's efficacy and safety.

Minimizing heat generation during milling is essential, as excessive heat can alter the material's properties, leading to fusion or agglomeration. Prevent these undesirable effects with equipment that reduces friction and maintains precise particle size control, guaranteeing the final product meets the required specifications.

A detailed PSD analysis is critical to verify the achievement of the optimal characteristics after milling. Methods such as sieving ensure quality control throughout this process.

The CPS Line conical calibrating mill from PAT Group offers a highly effective solution for achieving precise and controlled milling. This versatile equipment allows for the accurate calibration of a wide range of materials, ensuring uniform particle size distribution and improving the quality of the final product.

Integrating the CPS Line mill into your production process guarantees uniform PSD, optimizes process efficiency, minimizes the risks associated with heat generation, and enhances product quality and performance.