The importance of liver and digestibility in animal production.

Liver functions

The liver is the organ that coordinates the metabolism of fats, carbohydrates, and protein, with the aid of the?circulatory system, the?lymphatic system, and the endocrine. It plays a vital role in the metabolism and circulation of nutrients and the detoxification of toxic metabolites and xenobiotics (Chiang, 2017). The liver is a metabolically active organ that utilizes carbohydrates for the synthesis of cholesterol and fatty acids, and stores glucose as glycogen and free fatty acids as triglycerides (Chiang, 2017). Thus, a healthy liver is crucial to protein, carbohydrate, and fat metabolism. Inflammatory, immune-mediated, and neoplastic liver diseases occur more frequently as animals age.?

Nutraceuticals such as vitamin E, milk thistle extracts, S-adenyl methionine, and L-carnitine can play a significant role in ameliorating oxidative stress.

Important functions performed by the liver:

• Biliary secretion.
• Detoxification of toxic molecules or substances (e.g., drugs)
• Metabolism of carbohydrates,
• Lipid metabolism synthesizes lipoproteins, cholesterol, and phospholipids
• Amino acid metabolism,
• Concerning the immune response, it has antigen-presenting cells and many lymphocytes. Part of the proteins it synthesizes are precisely immune effectors, hence its importance in the immune response and the close relationship that the liver has with immunosuppression

However, high production performance makes animals prone to suffer from hepatic stress, making the organ more susceptible to different challenges, such as mycotoxins, free radicals, infectious agents, and diets with an inadequate protein-energy ratio that ends up causing the fatty liver syndrome. All these challenges are linked to insufficient feed management and nutritional imbalances.

One of the most important aspects of animal production is the digestibility of the animal. Protecting and promoting a healthy gut ensures a healthy animal that utilises the nutrients, proteins and energy for growth and development rather than illness. The growing period is the most critical as the young animals experience stress and development in a short amount of time which influences the gastrointestinal tract.

DIGESTABILE?

The Digestabile range from Bupo Animal Health is a uniquely formulated product range available for Poultry, Ruminants and Swine. ? These products consist of extracts from the milk thistle plant (Silybum marianum) and Choline Chloride ? Digestabile P, LA and S is used to increase profitability in production animals through improvement in the liver function

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DIGESTABILE L?

DESCRIPTION:

DIGESTABILE L? is an antitoxic liver protector water-soluble solution. It stimulates bile secretion and helps eliminate fat due to its choleretic and lipotropic properties.

?PRESENTATION:?Water-soluble liquid

?INDICATIONS:

1. Optimizes economic performance
2. Assists in recovery from the fatty liver syndrome in layers and breeders
3. Alleviates signs of mycotoxins/other intoxications that affect the liver and other organs.

DIGESTABILE-P?

DESCRIPTION:

DIGESTABILE-P??feed additive premix is a natural product comprising herbal extracts and choline chloride. It is a proprietary hepatomodulator, hepatoprotector and natural performance enhancer to optimize livestock’s economic performance by keeping animals healthy and productive.

PRESENTATION: Feed Additive Premix

INDICATIONS:

1. DIGESTABILE-P??improves the feed conversion rate, by means of its choleric and lipotropic properties that stimulate bile secretion and increase fat mobilization.
2. DIGESTABILE-P??is appropriate for use in poultry and ostriches.

DIGESTIBLE LA?

DESCRIPTION:

DIGESTIBLE LA? feed additive premix is for large animals to improve the feed conversion rate, by means of its choleretic and lipotropic properties that stimulate bile secretion and increase fat mobilization.

PRESENTATION:?Feed Additive Premix

INDICATION:

1. DIGESTIBLE LA? is a proprietary liver modulator and liver protector premix powder that was developed to optimize the ruminants economic performance by keeping them healthy and productive
2. For production support in dairy cattle during the transition period and when animals are introduced into the feedlot.

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BENEFITS OF DIGESTABILE LA? FOR CATTLE INCLUDE:

• Improved liver function
• Increased performance and productivity of dairy and beef cattle
• Aids with increased milk protein and a milk fat
• Reduces fatty liver ketosis and abomasal displacement
• Reduces the incidence of the fatty liver syndrome
• Assists with reproductive performance
• Assists with increased average daily gain
• Assists with increased Feed Conversion Ratio (FCR)

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DIGESTABILE S?

?DESCRIPTION:

DIGESTABILE S? is a proprietary antitoxic liver modulator and liver protector that was specially developed for swine to optimize their economic performance by enhancing feed conversion and utilization.

?PRESENTATION:?Feed Additive Premix

?INDICATIONS:

DIGESTABILE S? stimulates bile secretion and bile flow, thus preventing bile stagnation, gallstone formation and bile-induced liver damage. The secretion of bile increases the rate of fat digestion and elimination as well as the absorption of fat-soluble vitamins.

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?References

Chiang, J. (2017). Liver Physiology: Metabolism and Detoxification. https://www.researchgate.net/publication/271910276_Liver_Physiology_MetaboLism_and_Detoxification.

The Liver, the Cornerstone of Livestock Performance. https://www.natual-techna.com/en/zootechnical-performance/experts/toxins-liver-farm