Imaging Transgenic Nude Mice Expressing Spectrally-distinct Fluorescent Reporters

The first transgenic mice were created in the 1970s. Today, transgenic mice with fluorescent reporters are used to study a variety of biological states and diseases. Transgenic green fluorescent protein (GFP), red fluorescent protein (RFP), and cyan fluorescent protein (CFP) nude mice were previously developed in the AntiCancer Inc. laboratory. In the present study, researchers demonstrate imaging of transgenic nude mice with spectrally-distinct fluorescent reporters expressing GFP, RFP, or CFP, with single-nanometer-tuning laser fluorescence excitation using one instrument.

The UVP BioSpectrum Advanced is an all in-one BioImaging system with in vivo imaging capabilities for sample documentation and analysis, including in vivo animal imaging, plant imaging, chemiluminescence, NIR, and fluorescence. This all-in-one system is perfect for any lab within research institutions, medical facilities, academic research institutions, pharmaceutical companies, amongst others.

Features:

• Camera:?Choose between two deeply cooled camera options, including a 6.1MP fluorescence-focused sensor and a 1.05 MP fluorescence/bioluminescence-focused sensor
• Illumination:?Fully loaded with overhead laser bars in blue, green, red,?NIR,?violet (405nm) and white light
• Filter Wheel:?6-position automated filter wheel on a convenient slide-out tray; RFID-tagged filters for automatic software detection
• Motorized Lift:?Quickly adjust the motorized platform tray height to the desired position for optimized image capture
• VisionWorks? Software:?Powerful VisionWorks? software allows flexibility of creating custom one-touch workflows or using preinstalled one-touch application templates
• Free application training available with each purchase
• Choice of warming plate, UVP UV light transilluminator, or UVP Visi-Blue transilluminator
• Optional accessories available for purchase include UVP Anesthesia Kit, white and blue converter plates, and 3D animal imaging modules

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