Identification of a new class of thermolabile psychoactive compounds, 4-substituted 2-(4-X-2, 5-dimethoxyphenyl)-N-[(2-hydroxyphenyl)methyl]ethanamine
Forensic Chemistry
Available online 19 July 2020, 100266
In Press, Journal Pre-proofWhat are Journal Pre-proof articles?
Identification of a new class of thermolabile psychoactive compounds, 4-substituted 2-(4-X-2, 5-dimethoxyphenyl)-N-[(2-hydroxyphenyl)methyl]ethanamine (25X-NBOH, X= Cl, Br, or I) by gas chromatography-mass spectrometry using chemical derivatization by heptafluorobutyric anhydride (HFBA)
Benny J.LumaThomas A.BrettellbJoseph J.BrophycD.Brynn Hibbertc
https://doi.org/10.1016/j.forc.2020.100266Get rights and content
Highlights
?
Paper describes method which can expand the analytical ability of traditional gas chromatography-mass spectrometry (GC-MS)
?
Addresses concerns with specific compounds that are thermal labile such NBOHs and amphetamines.
?
HFBA chemical derivatization is extremely sensitive, robust and reproducible and is a great consideration as a confirmatory method.
?
This HFBA method can be applied to compounds such as phenethylamines, substituted cathinones or other forensic significant compounds.