i3S Inside Stories

i3S Inside Stories

Highlights from August 2024


i3S study uncovers blood alteration that predicts Crohn's Disease

The i3S team, led by researcher Salomé Pinho (centre), worked in collaboration with Mount Sinai Hospital (New York) and the US Department of Defence.

An international team of researchers, led by Salomé Pinho from i3S, has discovered a unique glycosylation signature in antibodies (immune system molecules) that is detectable in the blood many years before the onset of symptoms and the clinical diagnosis of Crohn's Disease. The revelation of this mechanism at a pre-clinical stage (before symptoms and diagnosis) paves the way for the identification of a biomarker capable of predicting the onset of the disease and preventing it.

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i3S project is one of the winners of the National Cancer Hub Competition

Daniel Ferreira from the group Expression Regulation in Cancer

The “HD CHIP” project, led by Daniel Ferreira, was one of the winners in the inaugural NCH-PT 2024 Competition. Organised by the National Cancer Hub-PT (NCH-PT), which is coordinated by the Agency for Clinical Research and Biomedical Innovation and the Directorate-General for Health through the National Programme for Oncological Diseases.

Focusing on Hereditary Diffuse Gastric Cancer (HDGC), which affects around 50 thousand people each year, Daniel Ferreira’s project aims to enhance early diagnosis and reduce treatment-related morbidity, while advancing a more personalised approach.

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One of the best doctoral theses in cancer is from the i3S

Diana Pádua and Raquel Almeida from the Differentiation & Cancer Group

Diana Pádua, former student of the Doctoral Program in Biomedical Sciences at ICBAS, whose research was developed at i3S under the guidance of researcher Raquel Almeida, leader of the Differentiation & Cancer group, was awarded one of the two “Best PhD Thesis” awards given by the journal Cancers.

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PhD student wins Racquel Legeros award

Mariana Magalh?es' project is guided by i3S researcher Cristina Barrias and co-supervised by Hernando A. del Portillo, from the University of Barcelona, and Riccardo Levato, from the University of Utrecht.

Mariana Magalh?es, a student in the Doctoral Program in Biomedical Engineering at FEUP and carrying out research in the “Bioengineered 3D Microenvironments” group, was awarded one of the two Racquel Legeros Awards, granted annually to two doctoral students in the area of biomaterials and regenerative medicine by the European Society for Biomaterials (ESB). The award will allow the young researcher to develop part of her research project at the Regenerative Medicine Center Utrecht, in the Netherlands.

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Grant awards recognize the quality of the work of young researchers

Beatriz Pereira, Gabriel Oliveira, Elisabete Teixeira, Inês Vilela de Sousa (left to right)

Over the last two months, several young researchers from the i3S have seen their work recognised internationally. Winning grants, whether to present papers at leading events or to undertake internships abroad, is a unique opportunity that should be fully exploited.

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