Hundreds of people have died! Multiple countries have issued epidemic warnings!

The latest report from the Disease Control Department of the Ministry of Health in Thailand shows that from the beginning of 2023 to September 13, a total of 91979 cases of dengue fever infection were found in Thailand, with a total of 84 deaths.

Recently, confirmed cases of dengue fever in Vietnam have rapidly increased. From September 4th to 10th, 2023, there were 5180 confirmed cases in Vietnam, including 1 death case (in Heping Province). The number of confirmed cases in Hanoi City reached 2010, nearly doubling from the last week of August. Since the beginning of the year, there have been a total of 81808 confirmed cases in Vietnam, including 23 deaths.

According to data released by the Bangladesh General Administration of Health Services on September 16th, as of that day, the country has reported a total of 164562 dengue fever cases and 804 deaths since the beginning of this year, including 211 deaths in September. The World Health Organization says this is the most severe dengue fever outbreak on record in the country.

According to the Singapore Environment Agency——

On September 20, 2023, according to the Singapore Environment Agency (NEA), a total of 259 cases of dengue fever (locally known as "bone pain fever") were detected in Singapore last week, with an increasing number of cases.

Introduction to Dengue Fever

Dengue fever is an acute mosquito borne infectious disease caused by the dengue virus, mainly transmitted through the bites of Aedes aegypti or Aedes albopictus. The incubation period is 3 to 15 days, most of which are 5 to 8 days. The clinical manifestation is acute onset, ranging from mild fever to high fever, accompanied by severe headache, muscle and joint pain, and rash, and flushing of the face, neck, and chest. In severe cases, death can be caused by shock or other important organ damage. According to the World Health Organization (WHO), in recent years, dengue fever has become the fastest spreading and most widespread infectious diseases, with 100 million to 400 million cases infected every year.

Dengue virus is a single stranded positive stranded RNA virus belonging to the flaviviridae family, which is resistant to low temperatures. Currently, four serotypes of dengue virus (DENV-1, DENV-2, DENV-3, and DENV-4) have been isolated, all of which are pathogenic. The rehabilitation of patients infected with a certain serotype is believed to provide lifelong immunity to that serotype, but the cross immunity to other serotypes after recovery is only partial and temporary. Secondary infections (secondary infections) of other serotypes increase the risk of developing severe dengue fever and death.

Laboratory testing of dengue fever (partial)

1. WHO laboratory diagnostic guidelines for detecting dengue fever and Zika virus

1) Testing process for suspected or symptomatic patients (non pregnancy)

2) Testing process for suspected or symptomatic patients (pregnancy)

2. Laboratory diagnostic guidelines for dengue fever detected by European CDC

3. Laboratory diagnostic guidelines for detecting dengue fever in the Americas region

4. Laboratory diagnostic guidelines for detecting dengue fever in Southeast Asia