Hundreds Blood Pressure Genes Identified: Blood Pressure Digest #39

By popular demand, we start answering questions that so many pose on social media: how to recognize symptoms of high blood pressure in women, when is blood pressure high enough to go to the hospital, how to avoid falls when blood pressure is too low, what is the best time of the day to take blood pressure medications, can leg pains be a sign of poor blood flow?

Further to the Q&A, this new issue of the Blood Pressure Digest has 25 news on blood pressure related research, medications, treatment and management, lifestyle and nutrition. In the Research section, read about 100 identified blood pressure genes, in the Medications - about the drug that shows promise against resistant hypertension, in Treatment & Management - about new efficient adherence programs, based on telemonitoring and mobile apps, in Lifestyle - about signs and symptoms you should not ignore, in Nutrition - about blood pressure friendly snacks, chocolate, and vitamins to avoid with hypertension.?

Q&A

How to Recognize the Symptoms of High Blood Pressure in Women?

According to Medical News Today, high blood pressure affects approximately one in three adults in the United States. However, symptoms can often go unnoticed, especially in women. The article explains that common symptoms of high blood pressure in women include headaches, shortness of breath, nosebleeds, and fatigue. It also highlights that women who are pregnant or taking hormone replacement therapy may be at a higher risk for developing high blood pressure. Therefore, it is crucial for women to be aware of these symptoms and regularly monitor their blood pressure. Prompt diagnosis and treatment can help prevent serious complications such as heart disease and stroke.?

Dr. Nieca Goldberg, a cardiologist and Director of the New York University Center for Women's Health, said: "Understanding the symptoms of high blood pressure in women is essential in order to take appropriate action and reduce the risk of long-term health consequences."

When is Blood Pressure High Enough to Go to the Hospital?

According to a story published by Verywell Health, it is crucial to know when high blood pressure warrants a trip to the hospital. Understandably, there is no specific number that indicates an immediate need for emergency care, but there are certain symptoms that should not be ignored. Symptoms such as chest pain, severe headache, shortness of breath, vision changes, and weakness or numbness in the face, arm, or leg on one side of the body could be signs of a hypertensive crisis. In such cases, seeking immediate medical attention is vital to prevent serious complications. It is recommended to monitor blood pressure regularly, follow prescribed medication regimen, and maintain a healthy lifestyle to keep blood pressure in check.

Dr. James Beckerman, a cardiologist and Medical Director of Prevention at Providence Hospital Heart Institute in Portland, Oregon, said: "A hypertensive crisis can lead to serious problems, including heart attack, stroke, kidney failure, or damage to other organs.”

How to Avoid Falls When Blood Pressure Is Too Low?

According to The Irish News, low blood pressure can increase the risk of falls, particularly in older adults. The article highlights the importance of maintaining proper blood pressure levels to prevent falls and provides practical tips. These include staying hydrated, avoiding sudden movements, using assistive devices such as walking aids, and exercising regularly to improve muscle strength and balance. It also emphasizes the significance of regular check-ups and medication adjustments under the guidance of healthcare professionals. Falls can lead to serious injuries, so taking steps to manage low blood pressure is crucial for maintaining overall health and well-being.

What's the best time of day to take blood pressure medication?

According to the Mayo Clinic, the best time of day to take blood pressure medication may vary depending on the type of medication prescribed. Generally, it is advised to take medication at the same time every day to maintain consistent blood pressure control. However, for specific types of medication, such as diuretics or beta blockers, taking them in the morning may be more effective due to their impact on the body's natural circadian rhythm. On the other hand, medications that have a shorter duration of action, like ACE inhibitors, may be more effective when taken in the evening. The key is to consult with a healthcare provider to determine the optimal timing for blood pressure medication based on individual needs.

Dr. Robert Sheeler, Medical Editor-in-Chief at Mayo Clinic said: "Taking blood pressure medication consistently and at the right time can improve its effectiveness and help control blood pressure."

Can Leg Pains Be a Sign of Poor Blood Flow?

According to The Times Free Press, leg pains can indeed be a symptom of poor blood flow, particularly in individuals with high blood pressure. A study published in JAMA Internal Medicine found that people with high blood pressure were more likely to experience leg pain during exercise. This is because high blood pressure can lead to the narrowing of blood vessels, reducing blood flow to the lower extremities. It is important for individuals with leg pain and high blood pressure to consult with their healthcare professionals to determine the underlying cause and appropriate treatment.

Dr. Christie M. Ballantyne, a Professor at Baylor College of Medicine , stated, "Recognizing the relationship between high blood pressure and leg pain is crucial for timely diagnosis and management."

RESEARCH

Hundreds of Blood Pressure Genes Identified

According to LabPulse, researchers have identified hundreds of genes associated with blood pressure, providing a foundation for the development of new drugs to treat hypertension. The study involved analyzing genetic data from over one million individuals and identified 535 genes related to blood pressure regulation. These genes are involved in various biological processes, including kidney function, hormone signaling, and blood vessel constriction. Understanding the genetic basis of blood pressure regulation could lead to the development of more personalized treatments for hypertension, as well as the discovery of novel drug targets. The findings highlight the complex nature of blood pressure regulation and the potential for precision medicine approaches in managing hypertension.

“Our results … have potential to enable new preventative and therapeutic opportunities for hypertension with wider implications for cardiovascular health,” Dr. Patricia Munroe, co-author of the paper and Professor of molecular medicine at Queen Mary University of London, said.

High Blood Pressure When Lying Down Increases Heart Complication Risks

According to the American Heart Association, a new study suggests that individuals with high blood pressure while lying down may be at a higher risk of heart health complications. The study found that people with nighttime blood pressure levels that remained high while lying down had an increased risk of heart damage, heart failure, and cardiovascular events. This research emphasizes the importance of monitoring blood pressure not only when sitting or standing but also while lying down. It is crucial for healthcare providers to consider this additional measurement to better assess an individual's risk for heart-related complications. Further studies are needed to confirm these findings and determine the optimal management strategies for patients with high blood pressure.?

"Nocturnal blood pressure may be an important and useful tool for assessing cardiovascular risk in patients with hypertension." Dr. Kazuomi Kario , Professor and Chairman of Cardiovascular Medicine, 自治医科大学 , Japan, said.

Untreated hypertension in those 60+ raises dementia risk by 42%

New Atlas reports: Untreated high blood pressure in people aged over 60 increases the risk of dementia, according to a study published in the European Heart Journal. The study tracked the blood pressure levels of over 8,500 people aged 50 and older for an average of 13 years. It found that individuals who had untreated high blood pressure in their 60s had a 49% higher risk of developing dementia compared to those with normal blood pressure. The risk remained significant even after controlling for other factors such as age, sex, education level, and other health conditions. The study highlights the importance of managing blood pressure levels, especially in older adults, to potentially reduce the risk of dementia later in life.?

Dr. Katarzyna Kostka-Jeziorny, a researcher at the Medical University of Gdansk in Poland, said: "Effective blood pressure management in middle-aged and older individuals may reduce dementia risk later in life."

MEDICATIONS

Investigational Drug Shows Promise For Resistant Hypertension

Lorundrostat, an investigational medication, has shown potential efficacy in treating uncontrolled and resistant hypertension, according to the results of a phase 2 trial, Patient Care reports. The study found that patients who received lorundrostat experienced a significant reduction in their blood pressure compared to those who received a placebo. The medication works by blocking an enzyme that is involved in the production of a hormone that raises blood pressure. The trial involved patients with primary aldosteronism, a condition that can cause high blood pressure. The findings suggest that lorundrostat could be a promising treatment option for patients with uncontrolled and resistant hypertension. Further research is needed to confirm these results and evaluate the long-term safety and effectiveness of the medication.?

According to Dr. William Young Jr., a Professor of medicine and endocrinology at the Mayo Clinic, "These findings are an exciting development in the field of hypertension research and provide hope for patients with difficult-to-treat high blood pressure."

TREATMENT & MANAGEMENT

Doctors Often Neglect Proper Guidelines In Measuring Blood Pressure

According to a study published on WND, doctors may be measuring blood pressure incorrectly. The study found that healthcare professionals often fail to follow the proper guidelines for blood pressure measurement, leading to inaccurate readings. The researchers highlighted the importance of using the correct cuff size and positioning the patient's arm at heart level to ensure accurate results. The study suggested that these measurement errors could potentially lead to misdiagnosis and inappropriate treatment decisions. It is crucial for healthcare providers to adhere to the established protocols to obtain accurate blood pressure measurements and prevent potential complications.

“If blood pressure is only measured while people are seated upright, cardiovascular disease risk may be missed if not measured also while they are lying supine on their backs,” says lead study author Duc M. Giao, a researcher and a 4th-year MD student at Harvard Medical School.

GPs In the UK Help Control Patients' Blood Pressure Through Tech

According to Computer Weekly, general practitioners (GPs) in Slough, UK, are using technology to monitor and control their patients' blood pressure. The initiative involves providing patients with Bluetooth-enabled blood pressure monitors that can sync with their smartphones. The data collected is automatically shared with the GPs, who can then remotely monitor their patients' blood pressure and make necessary interventions if needed. This approach not only allows for continuous monitoring but also reduces the need for frequent clinic visits. The technology has been well-received by both patients and healthcare providers, as it empowers patients to take an active role in managing their blood pressure.?

Dr. Bharan Kumar , a GP at Bharani Medical Centre in Slough, said: “From the outset, patient and staff feedback has been positive, engagement high and hypertension outcomes have improved surprisingly fast.”?

Mobile Phones May Help Hypertension Management

Using mobile phones may help in managing high blood pressure, according to Mobile Marketing Watch. A study conducted by researchers at Northwestern University in Chicago found that participants who used a mobile app to track their blood pressure and receive personalized feedback showed significant reductions in their blood pressure levels. The app provided reminders to take medication, encouraged lifestyle changes, and allowed participants to input their blood pressure readings. The study concluded that mobile health technology has the potential to greatly improve the management of hypertension.

"Using mobile phones as a tool to track blood pressure readings and receive personalized feedback may help individuals better manage their blood pressure and improve their overall health," said Dr. Stephen Persell, lead author of the study.

Bilingual Program Successfully Controls Blood Pressure in Underserved Groups

According to Patient Care Online, a remote bilingual program has shown effectiveness in controlling blood pressure among underserved populations. The study conducted at the The University of Texas Health Science Center at Houston (UTHealth Houston) involved Hispanic patients with uncontrolled hypertension. The program utilized remote monitoring, education, and regular follow-up appointments conducted in the patients' preferred language, Spanish or English. After 12 months, the blood pressure control rates significantly improved, with 70% of patients reaching their blood pressure goals. This innovative approach has the potential to bridge the language and access gaps in healthcare, providing effective blood pressure management to underserved populations.

Dr. Karen Saban, Associate Dean for Research at Loyola University Chicago Marcella Niehoff School of Nursing said: "The findings highlight the importance of culturally tailored and language-specific interventions in hypertension management, particularly for underserved populations."

LIFESTYLE

Morning Habits That Increase Blood Pressure

According to a report on MSN, certain morning habits could significantly raise blood pressure levels. Doctors warn that skipping breakfast, having a cup of coffee before eating, and starting the day with a stressful event can all contribute to elevated blood pressure. Skipping breakfast can lead to higher stress hormone levels, while having coffee on an empty stomach can temporarily spike blood pressure. Additionally, beginning the day with a stressful event, such as rushing to work, can trigger the body's "fight or flight" response and increase blood pressure. These habits are important to consider, as consistently high blood pressure can increase the risk of heart disease and stroke. Therefore, implementing healthier morning habits, such as eating a balanced breakfast and practicing stress-reducing activities, is recommended.

Pranayama Breathing Can Help Control Blood Pressure

According to the Indian Express, practicing pranayama breathing exercises can help in controlling blood pressure. Pranayama is a form of yogic breathing technique that involves deep, slow breaths to promote relaxation and reduce stress.

A study conducted by researchers from the All India Institute of Medical Sciences Patna showed that regular practice of pranayama can significantly lower both systolic and diastolic blood pressure levels. The study involved participants with hypertension who practiced pranayama for 30 minutes daily for 12 weeks.

In Winter, Blood Pressure Is Higher and More Difficult to Manage

Medical News reports: Blood pressure is higher and more difficult to manage in winter, according to a new study published in the journal of the American Society of Hypertension. The research analyzed data from more than 25,000 individuals and found that both systolic and diastolic blood pressure tend to be higher during the winter months. The study also revealed that people with high blood pressure experience an even more significant increase during winter. Possible explanations for this phenomenon include cold temperatures, decreased physical activity, and changes in blood vessel constriction. It is essential for individuals with hypertension to be especially vigilant during the winter months and monitor their blood pressure levels regularly.?

Robert B. Barrett, the American Medical Association in Greenville, SC, and lead author of this study: “Despite the smaller degree of systolic blood pressure variation, we were surprised to observe a great degree of change in blood pressure control between winter and summer months.”

Worrying Sign After Exercise Could Indicate High Blood Pressure

According to a study published in the European Journal of Preventive Cardiology, experiencing dizziness after exercise could be a sign of high blood pressure, The Mirror reports.? Researchers found that individuals who felt lightheaded or dizzy following physical activity were more likely to have undiagnosed or poorly controlled hypertension. The study involved over 1,500 participants who completed a treadmill exercise test and were monitored for changes in blood pressure. Those who reported feeling dizzy had significantly higher systolic and diastolic blood pressure levels compared to those without symptoms. The findings highlight the importance of regular blood pressure checks, especially after exercise, as dizziness may be an early warning sign of cardiovascular issues.?

"There is a need for increased awareness among healthcare professionals and patients to recognize dizziness as an important symptom associated with high blood pressure, which should not be ignored," said Dr. Virend K. Somers, a cardiologist at the Mayo Clinic.

Subtle Signs Of High Blood Pressure You Shouldn't Ignore

According to The Daily Record, high blood pressure often doesn't present any obvious symptoms, making it difficult to detect. However, there are subtle signs that could indicate you have high blood pressure. These include frequent headaches, nosebleeds, dizziness, and shortness of breath. Other symptoms may include chest pain, blurred vision, and fatigue. It's important to monitor your blood pressure regularly, especially if you have risk factors such as a family history of hypertension, obesity, or a sedentary lifestyle. If you experience any of these symptoms, it's recommended to consult with a healthcare professional to measure your blood pressure and determine if further evaluation or treatment is required.

Dr. David Montgomery, a cardiologist at the University of Colorado School of Medicine , said: "It's crucial to be aware of these subtle signs because high blood pressure is a silent killer that can lead to serious health complications if left untreated."?

Not Enough Sleep Is The Worst Habit for Blood Pressure

According to cardiologists, the worst habit for blood pressure is not getting enough sleep, Parade reports. A study published in the Journal of the American Heart Association reveals that consistently getting less than six hours of sleep per night significantly increases the risk of high blood pressure. The study found that adults who slept less than six hours had a 20% higher risk of developing hypertension compared to those who slept between six and eight hours. Lack of sleep can lead to the activation of the sympathetic nervous system, which regulates blood pressure. Additionally, sleep deprivation can disrupt the body's natural circadian rhythm, leading to hormonal imbalances that affect blood pressure regulation.

Dr. Susie Rockway, Senior Director of Research and Development at The Vitamin Shoppe said: "Getting enough sleep is crucial for maintaining healthy blood pressure levels."?

NUTRITION

5 health benefits of consuming lemongrass tea

According to Times of India, consuming lemongrass tea can provide several health benefits. Firstly, it may help to lower blood pressure due to its diuretic properties. Secondly, lemongrass tea is rich in antioxidants that can reduce inflammation and promote heart health. Additionally, it may aid in digestion by reducing bloating and indigestion. Moreover, the tea is believed to have antimicrobial properties that can boost the immune system. Lastly, lemongrass tea is known for its calming effects and may help to reduce anxiety and stress levels. Overall, incorporating lemongrass tea into your diet can offer multiple benefits for your health.

Dandelion Tea May Help Lower Blood Pressure

According to Cleveland Clinic, dandelion tea may have benefits for lowering blood pressure. Dandelion tea is rich in compounds called phytochemicals that have been shown to have anti-hypertensive effects. These phytochemicals can help relax and widen blood vessels, improving blood flow and reducing blood pressure levels. In addition, dandelion tea is a natural diuretic, which means it can increase urine production and help reduce excess fluid and sodium in the body, both of which can contribute to high blood pressure. However, it is important to note that while dandelion tea may have potential benefits for blood pressure, more research is needed to fully understand its effects and determine appropriate dosage.

Meet The Flavonoid That Lowers Blood Pressure

Quercetin, a flavonoid found in various fruits and vegetables, may have a positive impact on heart health, according to a report on Yahoo Lifestyle. Quercetin has been studied for its potential to lower blood pressure, reduce inflammation, and improve overall cardiovascular health. It has been found to have antioxidant and anti-inflammatory properties, which can help protect blood vessels and reduce the risk of heart disease. While more research is needed, incorporating quercetin-rich foods such as apples, berries, and citrus fruits into your diet may help support a healthy heart.

Dr. Linda Anegawa, the Medical Director at the Hawaii Pacific Health Medical Group suggests: "Including quercetin-rich foods in your diet, along with other heart-healthy habits, can provide potential benefits for your cardiovascular health."

Healthy snack cuts the silent killer

According to the Daily Record, a study has found that consuming a handful of nuts each day can significantly reduce blood pressure. The study, conducted by researchers from 英国伦敦大学 - 伦敦国王学院 and 英国帝国理工学院 , analyzed the data of over 4,000 adults and found that those who ate nuts regularly had lower blood pressure compared to those who did not. It is believed that the high levels of healthy fats, fiber, and minerals in nuts contribute to the blood pressure-lowering effect. Hypertension affects millions of people worldwide and is a major risk factor for cardiovascular diseases. Incorporating nuts into one's diet could be a simple and effective way to manage blood pressure levels.?

Dr. Alasdair Rankin, Research Director at Blood Cancer UK , said: "This study adds to the growing body of evidence that consuming nuts is beneficial for cardiovascular health."

Fact or Fiction: Eating Chocolate is Good for You

According to Bloomberg, recent studies suggest that consuming chocolate in moderate amounts can have positive effects on blood pressure. Dark chocolate, in particular, contains flavanols which are known to relax blood vessels and improve blood flow. A study conducted on 35,000 people found that those who ate chocolate more frequently had lower blood pressure compared to those who consumed it less often. However, it is important to note that this research does not imply that everyone should start indulging in chocolate. The study does not establish a cause-and-effect relationship, and excessive chocolate consumption can lead to weight gain and other health issues. As always, moderation is key.?

Dr. Marc Penn, cardiologist and Director of Research at Summa Health in Akron, Ohio, said: "Although these findings are promising, more research is needed to fully understand the effects of chocolate on blood pressure and overall health."

10 herbs that will naturally reduce high blood pressure

According to DNA India, there are several herbs that can naturally help reduce high blood pressure. One of them is garlic, which has been shown to lower blood pressure levels. Another herb is basil, which contains compounds that can relax blood vessels and lower blood pressure. Hibiscus tea is also mentioned, as it has properties that can lower both systolic and diastolic blood pressure. Other herbs that can be beneficial include ginger, cinnamon, turmeric, and celery seed. However, it is important to note that these herbs should not replace prescribed medications without consulting a healthcare professional.?

The Health Benefits of Grapes: More Than Just Diabetes or Blood Pressure

According to an article in Moneycontrol, grapes offer a range of health benefits beyond managing diabetes and blood pressure. Rich in antioxidants, grapes can improve skin health by reducing signs of aging and preventing skin damage caused by UV radiation. The fruit also contains compounds that may help prevent certain types of cancer, such as colon and breast cancer. In addition, grapes can aid in weight management due to their low calorie and high fiber content. Moreover, the high water content in grapes contributes to hydration. Including grapes in your diet can provide a delicious way to promote overall health and well-being.

Vitamins to Avoid with High Blood Pressure

According to lifestyleasia.com, certain vitamins and supplements may have negative effects on individuals with high blood pressure. Vitamin E, for example, is known to thin the blood and may interfere with blood pressure medications. Similarly, fish oil supplements, which are rich in omega-3 fatty acids, can also thin the blood and may increase the risk of bleeding or interfere with blood pressure control. Another supplement to be cautious with is St. John’s wort, as it can interact with blood pressure medications and increase the risk of side effects. It is important for individuals with high blood pressure to consult with their healthcare provider before taking any vitamins or supplements, as they can provide guidance on the best options for their specific condition.

Surprisingly Common Foods for a Healthy Heart

According to CNET, there are five common foods that can contribute to a healthy heart and help lower blood pressure. These foods include berries, leafy greens, fatty fish, nuts, and whole grains. Berries are packed with antioxidants that can reduce inflammation and improve blood flow. Leafy greens, such as spinach and kale, are rich in potassium which can help lower blood pressure. Fatty fish like salmon and tuna are high in omega-3 fatty acids that can reduce inflammation and improve heart health. Nuts, like almonds and walnuts, contain healthy fats, fiber, and antioxidants that can benefit heart health. Lastly, whole grains, such as oatmeal and quinoa, are high in fiber and can help reduce the risk of heart disease.

Converting white fat to brown reduces blood pressure. In Mice

New Atlas reports: Converting white fat to brown reduces blood pressure in mice, according to a study published in the journal "Cell Reports". Researchers at the University of Cambridge found that stimulating the production of brown fat cells in mice led to lower blood pressure levels. Brown fat is a type of fat that generates heat by burning calories, while white fat stores excess energy. The study used a drug called RO9051 to increase the production of brown fat cells. The mice that received the drug had lower blood pressure and improved glucose tolerance compared to the control group. The findings suggest that converting white fat to brown fat could be a potential strategy to treat hypertension in humans.?

According to Professor Toni Vidal-Puig, from the University of Cambridge, "This study provides further evidence that manipulating brown fat could be a new therapeutic approach for obesity-related diseases, such as hypertension."

Fall Produce for Heart Health

According to Verywell Health, incorporating fall produce into your diet can have positive effects on heart health. Foods such as pumpkins, apples, and sweet potatoes are rich in vitamins, minerals, and fiber that can help lower blood pressure and reduce the risk of heart disease. Apples, for example, contain antioxidants and soluble fiber, which can help lower cholesterol levels. Pumpkins are packed with potassium, which is known to lower blood pressure, while sweet potatoes are a good source of fiber and vitamin C. Including these seasonal fruits and vegetables in your diet can provide a natural way to support heart health and maintain optimal blood pressure levels.