How Reaxys Target and Bioactivity data answers your drug discovery questions

The drug discovery and development process is filled with challenging questions. Reaxys Target and Bioactivity data can provide insights to help you find the answers. Here are 5 important questions that researchers must often ask, and how Reaxys can help.

How do I review SAR data for compounds in a patent?

From hit-to-lead to lead optimization, Reaxys empowers you with critical target and bioactivity insights. You can gain a competitive edge and accelerate your design process by accessing structure-activity relationship (SAR) data, toxicology, and efficacy information across more than 48 million bioactivity data points in Reaxys. Get ready to streamline your compound design process and watch this video to see how easy it is to gather structure-activity relationship data for every compound in a patent

Will my compound cause off-target effects?

If you need to assess off-target interactions with comprehensive extracted targets data, dive into this insightful video featuring Scott Newman, PhD, Elsevier Customer Consultant, as he guides you through evaluating interactions between specific scaffolds and targets.

Could my scaffold be cardiotoxic?

In drug discovery, understanding a compound's potential impact on vital targets like hERG or its influence on cardiac pathways is crucial to avoid costly setbacks. With Reaxys Target and Bioactivity data, you can dive deep into comprehensive, expertly curated datasets. Click here to see how Reaxys can help you assess cardiotoxicity risk and make data-driven decisions with confidence.

Is my scaffold metabolically stable?

Understanding how a scaffold interacts with metabolic enzymes and predicting ADME (absorption, distribution, metabolism, and excretion) properties early can save significant time and resources. Reaxys Target and Bioactivity data enables you to explore meticulously curated insights into bioactivity and enzyme activity helping you design better compounds faster. Click here to see how to check the metabolic stability of your scaffold with trusted research data using Reaxys.

Can I prevent adverse drug reactions in the early stages?

This is a crucial question for drug discovery teams. Identifying potential off-target effects and toxicity risks early can mean the difference between a breakthrough therapy and an expensive failure. Reaxys Target and Bioactivity data offers access to expertly curated information on:

• Biological targets
• Substances with bioactivity data
• Cells lines from 102K species

This data empowers you to build models that can help predict adverse reactions before they happen. Early insights lead to smarter decisions—and safer outcomes for patients. You can learn more in this informative case study.

Find out more, including how to get in touch with Reaxys experts about your research questions, here.

?

?

?