How to Prevent And Control The Threat of T-2 Toxin in Feed?

T-2 toxin is a sesquiterpene compound with strong thermal stability and can persist indefinitely in feed. Moldy corn may be the main source of T-2 toxin. When the humidity is 40-50% and the temperature is 3- The ability to produce toxin is strongest in 7℃ environment!

T-2 toxin can directly irritate the skin and mucous membranes, and can penetrate epithelial tissue. Symptoms of animal poisoning generally include loose stools, diarrhea, slow eating, weight loss, sub-standard weight, decreased antibodies, and susceptibility to other diseases.

After T-2 toxin enters the animal's body. Metabolic reactions can occur in the liver and intestines of animals. Studies have shown that the metabolism of T-2 toxin in chicken excreta and its tissues shows that trace amounts of the toxin are found in the lungs, and no original traces of the toxin are found in the heart and kidneys. Drugs and metabolites, except for a large number of metabolites found in the liver, most of the metabolites are present in the feces.

T-2 toxin increases the limit in plant feed ingredients; pig compound feed and poultry compound feed are described as pig and poultry compound feed, and the limit standard is reduced to 0.5ppm.

The poisoning symptoms of T-2 toxin are relatively similar to those of aflatoxin. Bleeding and liver and stomach damage will occur. However, there is one unique poisoning symptom of T-2 toxin. Remember, the gastric mucosa and skin are peeled off. An autopsy revealed necrotic and hemorrhagic damage to the gastrointestinal tract, liver and kidneys, and gastrointestinal mucosal edema and bleeding, especially the damage to the duodenum and jejunum was most obvious.

It should be emphasized here that when poultry is poisoned by T-2 toxin, oral mucosal ulcers, gizzard ulcers and erosions, intestinal bleeding, spleen and other immune organs are significantly atrophied, and the suborbital sinus of chickens is swollen with white mucus that is purulent or cheese-like. Secretions, some sick chickens also have symptoms of airsacculitis.

When poultry bleeding T-2 toxin poisoning is found, the feed, litter, etc. should be checked immediately, and bile acids should be added to the feed together with some antioxidants such as vitamins B and E to enhance the immunity and antioxidant function of the chickens.

Bile acids promote the metabolism of T-2 toxin by activating its receptors, increasing the expression of metabolic enzymes and enhancing antioxidant capacity, thereby reducing the levels of oxidative damage, inflammatory reactions and liver damage. Therefore, bile acids can effectively protect against T-2 toxin damage.