Is Gluten a Dormant Poison Killing Your Brain? ??

Dear Readers,

While affecting 1% of the world's population, Celiac Disease affects 1 in 96 North Indians, while being uncommon in the North East or South India, all due to dietary patterns (tradition and culture matters!)

But what is celiac disease?

They don't want you to know sometimes celiac disease manifests as a neurological condition, which can significantly improve if a gluten-free diet is adopted right away.

In celiac disease, the ingestion of gluten (a protein found in wheat, barley, and rye) triggers an autoimmune response.

This response involves the production of autoantibodies that can cross-react with various tissues, including those in the nervous system.

The immune response can lead to

neuroinflammation - inflammation in the nervous system

ataxia - loss of coordination

neuropathy - nerve damage and other neurological deficits.

In patients with gluten ataxia (where the immune system attacks the cerebellum, the part of the brain responsible for coordination and balance causing gait disturbances and other motor control issues) antibodies against gliadin (a component of gluten) can be found.

These antibodies cross-react with neural tissue, contributing to cerebellar damage.

Simultaneously, a cause-and-effect game takes place too.

Celiac disease often leads to malabsorption of essential nutrients in the small intestine. Deficiencies in vitamins and minerals, particularly B vitamins (such as B12 and folate), are common and can contribute to neurological symptoms.

As the gut heals, the absorption of B vitamins, zinc, and magnesium improves.

If you have a disturbed gut, but take supplements, you are pumping your body with something that can not be

Cut gluten out, you don't need it.

Early adoption of a gluten-free diet can prevent further neurological damage, stabilizing and sometimes reversing the progression of neurological manifestations. Many patients experience a significant reduction in neurological symptoms once gluten is eliminated from the diet. This can include improvements in coordination, balance, peripheral nerve function, and cognitive clarity.

A healthy gut can then absorb B vitamins which are crucial for maintaining the myelin sheath, the protective covering around nerve fibers. Deficiencies of the B-vits can result in demyelination, leading to neuropathy and other neurological issues as well.

Thank you for reading!

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Citations:

Makharia GK, Verma AK, Amarchand R, Bhatnagar S, Das P, Goswami A, Bhatia V, Ahuja V, Datta Gupta S, Anand K. Prevalence of celiac disease in the northern part of India: a community based study. J Gastroenterol Hepatol. 2011 May;26(5):894-900. doi: 10.1111/j.1440-1746.2010.06606.x. PMID: 21182543.

Ford RP. The gluten syndrome: a neurological disease. Med Hypotheses. 2009 Sep;73(3):438-40. doi: 10.1016/j.mehy.2009.03.037. Epub 2009 Apr 29. PMID: 19406584.