Get the Latest Insights into Neurodevelopment

1. Cellular Crosstalk in Neurodevelopmental Disorders

Deepen your understanding of the causes of neurodevelopmental disorders and explore the latest microscopy- and mutation-based methods to study extracellular mechanisms essential for human brain development.

In this webinar, you will learn about:

• How combining in vivo mouse models and in vitro human-derived neurons, cerebral organoids, and assembloids sheds light on the causes of neurodevelopmental disorders
• The molecular and cellular mechanisms involved in ventral progenitor proliferation and fate
• The migration and maturation of inhibitory neurons during human brain development

Live on Wednesday, April 24th, 2024.

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2. Unleash New Biological Insights with Innovative Glycoanalytics

Explore the current landscape of glycobiology. In this episode of Listen In, learn about innovative analytical methods for N- and O-linked glycosylation profiling from biological specimens, and discover how advances in glycoanalytics enable new insights into human glycobiology.

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3. Maxam–Gilbert Sequencing: What It Is and 3 Modern Applications

In the old days, Maxam–Gilbert sequencing was the DNA sequencing method of choice, but it has mostly been replaced by Sanger sequencing and Next-Generation methods. Hear why Maxam–Gilbert sequencing lost its popularity and why some researchers continue to use it.

>>Listen Now<<

Here's a funny thing I've seen in the lab—someone do 100 cycles of PCR.

The person was trying to introduce a point mutation using inverse PCR. After 28 cycles, there was no PCR product on their agarose gel. So they put the PCR reaction back on for a further 72 cycles.?

They got a PCR product and when they transformed, prepped, and sequenced it, it had the desired mutation!?

Sometimes, the silly approaches work.

-Thomas Warwick, Content Creator, Bitesize Bio