Generation of Site-Specific Knock-in Mouse as Fast as within 100 days

Advantages of TARGATT? Technology

1. High integration efficiency mediated by PhiC31 integrase reduces time and cost
2. Site-specific integration at a pre-selected genomic locus eliminates position effect and ensures high expression levels of the transgene
3. Integration at intergenic region ensures that no internal genes are interrupted
4. Single copy gene integration eliminates repeat-induced gene silencing and genomic instability
5. Site-specific integration allows a precise comparison of the effects of the transgenes among different lines.