The Flow State Apprentice #5
Image Credit: Aikido and the Harmony of Nature by Mitsugi Saotome

The Flow State Apprentice #5

Flow: The Synergy of Skill and Challenge

The conditions for entering flow include balancing challenges and actions with skills and clear, well-defined goals with quick feedback. To achieve flow, our skill set must be in balance with the challenge at hand.

#flowstate #flow #skill #challenge #synergy

Five Neuroprotective Mechanisms of CBD

Did you know that natural molecules and mixtures are more likely to participate synergistically when they affect more than a single biochemical pathway?

CBD exerts its neuroprotective effects through at least five different molecular mechanisms.

Five Neuroprotective Mechanisms of CBD

Molecular Targets of CBD in Experimental Models of Neurological Disease

1). Adenosine receptor subtype 2A

2). HT1A - Serotonin receptor subtype 1A

3). GPR-55 G protein-coupled receptor 55

4). TRPV-1; a ligand-gated ion channel: And lastly ...

5). A nuclear factor, known as PPAR-gamma

The authors state: "In conclusion, CBD, through multi-target mechanisms, represents a valid therapeutic tool for the management of epilepsy, Alzheimer's disease, multiple sclerosis, and Parkinson's disease."


How Adaptogen Herbs Modulate JNK1 to Affect Stress, Inflammation, and Cellular Health

Adaptogens are plants that increase tolerance to the effects of physical or mental stress and enhance endurance and performance.

One of many pathways that adaptogens influence is the Stress-Activated c-Jun N-terminal Protein Kinase 1: aka JNK1. This pathway is involved in the cellular stress response It has a role in regulating apoptosis (cell death), inflammation, and metabolic processes.

Dysregulation of JNK1 can lead to increased cellular damage, inflammation, and impaired cell survival mechanisms.


Topical CBD Protects Skin Cells from Damaging UV Radiation - Research Review

In this animal study, topical CBD protected skin exposed to damaging UVA and UVB radiation. Topical CBD improved the lipid profile of skin cells including keratinocytes, and also improved skin barrier status.

Changes in Lipid Profile of Keratinocytes from Rat Skin Exposed to Chronic UVA or UVB Radiation and Topical Application of CBD

Source: Changes in Lipid Profile of Keratinocytes from Rat Skin Exposed to Chronic UVA or UVB Radiation and Topical Application of Cannabidiol

Topical CBD improved the lipid profile of skin cells including keratinocytes, and also improved skin barrier status.


Research Review: Antioxidant Effects of CBD in the Hearts of Mice

The authors of this study showed that CBD treatment in mice markedly improves heart function, reduces oxidative and cardiac muscle cell death, and increases the function of mitochondria in the heart muscle.

Mitochondria produce energy for the cells. Improved mitochondrial function benefits health by increasing energy production, and assists in antioxidant protection by reducing oxidative stress.

The authors in this study state that CBD treatment in the mice “markedly improved heart function, reduced oxidative and cardiac muscle cell death”, and “increased the function of mitochondria in the heart”.

CBD Protects against Doxorubicin-Induced Cardiomyopathy by Modulating Mitochondrial Function and Biogenesis

Flow States - Mirror Neurons - Alter Egos - and the Unfettered Mind

In this video, professional storyteller Gregory Frye and I discuss flow states, and how they might be more easily accessed to enhance performance.

We also discuss the concept of mirror neurons in empathy, and how these might be involved in flow states, and the unfettering of our mind during performance-oriented tasks.

#flow #flowstate #performance #mirrorneurons #alterego #unfetteredmind #empathy


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To Reach Your Full Potential You Need a Fully Optimized Nervous System

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Dr. Jake F. Felice, N.D., L.M.P. Biography

Founder, Sweetwater Holistic LLC

Dr. Jake F. Felice, ND, LMP, provides world-class education experiences by speaking authentically about natural health, flow states, and whole-body wellness.

He is an author, clinician, educator, and consultant whose vision is to advance the science and practical application of natural medicines for medical and recreational markets worldwide.

He grew up in Western Pennsylvania and attended Penn State University, where he played varsity lacrosse and majored in psychology.

As a young man, Dr. Jake was fascinated with Asian cultures and spent five years in Japan, where he studied shiatsu, aikido, and tai chi. After his studies in Japan, Dr. Jake spent a year motorcycling through Thailand, Nepal, and India, where he studied traditional healing arts.

Dr. Jake’s educational materials foster connection with the natural world, enhance human potential, raise awareness, and bring attention to the therapeutic properties of botanicals, homeostasis, and synergistic principles in nature.

His Category 1 CME courses for doctors on the ECS have now been translated into four languages. Dr. Felice is the founder of Sweetwater Holistic Consulting LLC. His passion is coaching flow-state access for high-performing men in athletics and business. He also advises dietary supplement and cannabis companies regarding optimal botanical product development.

Dr. Felice has consulted for major cannabis companies, including Willie Nelson’s brand, Tilray Inc., Manitoba Harvest, Smith & Sinclair, WorldLink Medical, Cannabis Basics, Medical Marijuana 411, Seattle Central College, The National University for Natural Medicine, the University of Las Vegas Nevada, the Academy of Cannabis Science, and the American Academy of Cannabinoid Medicine. He educates doctors, nurses, and cannabis professionals, including creating AMA-approved CEU classes for physicians.?

As a consultant, advisor, and brand strategist, Dr. Felice provides scientific, marketing, public relations, and compliance advice for companies in emerging and existing cannabis markets.


I hope that you enjoy this week’s newsletter.? Please comment, like, and share with others.? Many thanks! -Dr. Jake

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Amazing journey through the transformative power of Flow State and the benefits of CBD! ???? Leonardo da Vinci once said - Simplicity is the ultimate sophistication. Your exploration simplifies complex concepts into valuable insights. Keep inspiring and sharing the wisdom! ?????

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Randy Eady

Wave Maker in the Sea of Tranquility

1 年

Flow, so nicely tied together, like a good rug! The abiding focus of flow is non-reactive-effects. As well as how these effects compare to those produced by movement healing. Dr. Jake F. Felice's understanding shows that to respond out of nothingness is most affable & leaves no residue. When action comes out of nothing it is so total its very totality is a circle: complete & finished. As a most famous dude (Bruce Lee) once circulated it, "Don't fear failure. Not failure, but low aim is the crime. In great attempts it is glorious even to fail." Life need not be practiced; life is to be lived. Life is not a drama -- you need not prepare; you need simply to abide. Like love, it come as it comes, & is spontaneous. Otherwise, you'll keep following directions until pretty soon you're passed it & life won't even be fun while it lasted ~~~Natalie G. ??

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Dr. Jake F. Felice

| Flow Therapy | Transformational Advice | End of Life Support | Founder at Sweetwater Holistic LLC | ?? Doctor of Naturopathy ?? | Change Agent | Scholar ??| Teacher | Wave Chaser |

1 年

I hope that you enjoy this week’s newsletter The Flow State Apprentice.? Please comment, like and share with others.? Many thanks!

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