Fatigue is Epidemic

Fatigue is Epidemic

We are currently experiencing a fatigue epidemic in Australia.?You are probably saying REALLY I would not have guessed that!?

Many people believe there is no cure for chronic fatigue, but I totally disagree.?We all have the ability to heal ourselves.?

I often hear this response:

As one of my patients said, “The doctor looked at me and said, ‘You’re young! You have no reason to be tired. You just need to exercise more.’?

One of the reasons why is that when we look at blood tests, they often fail to provide an answer for these patients, leaving them more tired, stressed out, and totally over it. Perpetually questioning why they are so tired when nothing shows up. However, when I run a frequency test, I receive more information and we can know very quickly why these symptoms are present. It's what I do automatically when I see new patients

In the meantime, most practitioners are in a desperate search for answers and this can often lead to a generalized diagnosis of Chronic Fatigue Syndrome (CFS), a debilitating disorder of unexplained, persistent, and/or relapsing fatigue that results in a significant reduction in occupational, social, and personal activities.?

Other diagnostic criteria for CFS includes:

  • Impaired memory or concentration that severely impacts daily functioning
  • Chronic or recurrent sore throat
  • Tender lymph nodes
  • Muscle and/or joint pain
  • Headaches
  • Unrefreshing sleep
  • Increased levels of fatigue after exercise

Although the exact cause of CFS is unknown until further investigation, there are several possible triggers that have been identified.?

These include chronic infections such as Epstein-Barr Virus (EBV), also known as glandular fever, and biotoxin exposure from tick bites { Lyme disease}, cold sore herpes, and human herpes virus 6 (HHV6), exposure to mould. Just to name a few.

These suspected infective agents trigger an immune cascade that leads to immune dysfunction,?chronic inflammation, hormonal imbalances, and oxidative stress.?

This in turn presents symptomatically with a wide range of symptoms.?

CFS is a complex condition that requires a comprehensive approach to treatment.?

Furthermore, there are other contributing factors from our modern lifestyles that are having an impact on our energy deficits:

  • Nutritional deficiencies include iron, B vitamins (especially B6, B12, and folate), Magnesium, and Zinc.
  • Dehydration is a common cause of fatigue, especially if you regularly consume coffee, tea, and/or alcohol.
  • An inflammatory diet high in refined carbohydrates i.e. take-out, sugar, and ‘white’ foods.
  • Chronic stress can offset a number of health conditions affecting the immune system, gut, mind, and thyroid health.
  • Thyroid disorders exhibit a wide range of metabolic symptoms including fatigue.
  • Gut dysbiosis and small intestinal bacterial overgrowth (SIBO) reduce nutrient absorption and are linked to a range of inflammatory and immune conditions.
  • Exposure to environmental and household toxins i.e. chemicals in your skin care products, household cleaners, pesticides and fertilizers, mould, heavy metals etc.
  • Electromagnetic field (EMF) exposure from mobile phones, telephone towers, Bluetooth devices, microwaves etc.
  • Insomnia and sleep disturbances

If any of this relates to you or someone you know, please get in touch with me,

Let's break the cycle and get your life back asap,

Much Love,?

Jayne Bryson, ND

Book a Discovery Call:

https://calendly.com/jaynebryson/15minute

References

1. Institute of Medicine. Beyond myalgic encephalomyelitis/chronic fatigue syndrome: redefining an illness.?www.ncbi.nlm.nih.gov/books/NBK274235/pdf/Bookshelf_NBK274235.pdf ?Accessed February 21, 2015.

2. Smith MEB, Nelson HD, Haney E, et al. Diagnosis and treatment of myalgic encephalomyelitis/chronic fatigue syndrome. evidence report/technology assessment No. 219. (Prepared by the Pacific Northwest Evidence-based Practice Center under Contract No. 290-2012-00014-I.) AHRQ Publication No. 15-E001-EF. Rockville, MD: Agency for Healthcare Research and Quality; December 2014.?https://effectivehealthcare.ahrq.gov/sites/default/files/pdf/chronic-fatigue_research.pdf . Accessed June 16, 2020

3. Henderson, TA. The role of antiviral therapy in chronic fatigue syndrome.?https://www.psychiatryadvisor.com/opinion/the-role-of-antiviral-therapy-in-chronic-fatigue-treatment/article/405424/ . Accessed May 17, 2020.

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6. Prusty BK, Gulve N, Govind S, et al.?Active HHV-6 Infection of cerebellar purkinje cells in mood disorders .?Front Microbiol. 2018 Aug 21;9:1955.

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8. Lerner AM, Beqaj SH, Deeter RG, Fitzgerald JT.?Valacyclovir treatment in Epstein-Barr virus subset chronic fatigue syndrome: thirty-six months follow-up .?In Vivo. 2007;21(5):707-713.

9. Kogelnik AM, Loomis K, Hoegh-Petersen M, et al.?Use of valganciclovir in patients with elevated antibody titers against Human Herpesvirus-6 (HHV-6) and Epstein-Barr Virus (EBV) who were experiencing central nervous system dysfunction including long-standing fatigue .?J Clin Virol. 2006;37(suppl 1):S33-S38.

10. LevyJ A, Ferro F, Greenspan, DLennette ET.??Frequent isolation of HHV-6 from saliva and high seroprevalence of the virus in the population .?Lancet?1990;335:1047–1050.

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15. Chaabane S, Harfouche M, Chemaitelly H, et al.?Herpes simplex virus type 1 epidemiology in the Middle East and North Africa: systematic review, meta-analyses, and meta-regressions .?Sci Rep.?2019;9(1):1136.

16. Woestenberg PJ, Tjhie JH, de Melker HE, et al.?Herpes simplex virus type 1 and type 2 in the Netherlands: seroprevalence, risk factors and changes during a 12-year period .?BMC Infect Dis.?2016;16:364.

17. Bradley H, Markowitz LE, Gibson T, McQuillan GM.?Seroprevalence of herpes simplex virus types 1 and 2–United States, 1999-2010 .?J Infect Dis.?2014;209(3):325-33.

18. Schreiner P, Harrer T, Scheibenbogen C, et al.?Human herpesvirus-6 reactivation, mitochondrial fragmentation, and the coordination of antiviral and metabolic phenotypes in myalgic encephalomyelitis/chronic fatigue syndrome .?Immunohorizons.?2020;4(4):201-215.

19. Barcelos IP, Troxell RM, Graves JS.?Mitochondrial dysfunction and multiple sclerosis .?Biology (Basel).?2019;8(2). pii: E37.

20. Kambe Y, Miyata A.?Potential involvement of the mitochondrial unfolded protein response in depressive-like symptoms in mice. ?Neurosci Lett.?2015;588:166-71.

21. Henderson TA, Morries LD.?Multi-Watt near-infrared phototherapy for the treatment of comorbid depression: an open label single arm study .?Front Psychiatry.?2017;8:187.

22. Reddy PH.?Mitochondrial dysfunction in aging and Alzheimer’s disease: strategies to protect neurons .?Antioxid Redox Signal.?2007;9(10):1647-58.

23. Vali S, Mythri RB, Jagatha B, et al.?Integrating glutathione metabolism and mitochondrial dysfunction with implications for Parkinson’s disease: a dynamic model .?Neuroscience.?2007;149(4):917-30.

24. Smits B, van den Heuvel L, Knoop H, et al.?Mitochondrial enzymes discriminate between mitochondrial disorders and chronic fatigue syndrome .?Mitochondrion.?2011;11(5):735-8.

25. Prusty BK, Gulve N, Chowdhury SR, et al.?HHV-6 encoded small non-coding RNAs define an intermediate and early stage in viral reactivation. ?Genom Med.?2018; 5;3:25.

26. Stevens S, Snell C, Stevens J, et al.?Cardiopulmonary exercise test methodology for assessing exertion intolerance myalgic encephalomyelitis/chronic fatigue syndrome .?Front Pediatr.?2018;4;6:242.

27. Kim SJ, Ahn DG, Syed GH, Siddiqui A.?The essential role of mitochondrial dynamics in antiviral immunity. ?Mitochondrion.?2018;41:21-27.

28. Tiku V, Tan MW, Dikic I.?Mitochondrial functions in infection and immunity .?Trends Cell Biol.?2020;30(4):263-275.

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34. Estévez-López F, Mudie K, Wang-Steverding X, et al.?Systematic review of the epidemiological burden of myalgic encephalomyelitis/chronic fatigue syndrome across europe: current evidence and EUROMENE research recommendations for epidemiology .?J Clin Med.?2020;9(5):E1557.

35. Ponting C, Sanchez-Pulido L, Nicoll-Baines K, et al. Analysis of data from 500,000 individuals in UK Biobank demonstrates an inherited component to ME/CFS.?https://mecfsresearchreview.me/2018/06/11/analysis-of-data-from-500000-individuals-in-uk-biobank-demonstrates-an-inherited-component-to-me-cfs/ . Accessed June 16, 2020.


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