Ex vivo TCE Assays Compliant with FDA Recommendations in Patient Samples

?? Advancing T Cell Engager (TCE) Research with Vivia Biotech

At Vivia Biotech, we're committed to excellence in T Cell Engager (TCE) research. We offer comprehensive assays meticulously aligned with key FDA recommendations to accelerate the development of innovative therapies.

?? Our Services Include:

? Patient Sample Access:

• Fresh samples for multiple indications (AML, MM, CLL, NHL, etc.)
• Extensive collection of frozen samples, fully molecular characterized
• Complete clinical data

? Native Environment Assays:

• Leveraging patented technology for a physiologically relevant approach

? Efficacy Assays via Flow Cytometry:

• Determining the recommended first in human dose (FIH)
• Exploring dual targeting strategies for additive or synergistic efficacy
• Cross-linking assays showcasing improved efficacy
• Evaluating interpatient variability through target expression of your TCE

? Immunotoxicity Evaluation:

• Selective killing and hematotoxicity assays
• CDC/ADCC assays to assess immunotoxicity potential
• Flow cytometric analysis of proliferation and activation markers
• Cytokine release assays

Join us in revolutionizing TCE development. Learn how Vivia Biotech can support your research and development initiatives.