Eupraxia Pharmaceuticals Initiates Phase 2 Study in Eosinophilic Esophagitis

-Represents second Phase 2 program for EP-104IAR, with initial data readout anticipated in H1, 2023-

Victoria, B.C. – October 12, 2022 - Eupraxia Pharmaceuticals Inc. (“Eupraxia” or the “Company”) (TSX: EPRX), a Phase 2 clinical-stage biotechnology company with an innovative drug delivery technology platform, today announced the initiation of a Phase 2 trial of EP-104IAR in adult patients afflicted with eosinophilic esophagitis (EoE), a rare disease that restricts the ability to swallow food and greatly impacts quality of life.

“EP-104IAR is designed to precisely deliver therapeutic levels of injected fluticasone propionate over an extended duration, which may help overcome some of the limitations of traditional oral steroids and provide longer and more stable disease remission and an improved quality of life for patients with EoE,” said Dr. James Helliwell, CEO of Eupraxia.?“On that basis, we are initiating a Phase 2, open-label clinical study in adult patients with data from the trial expected to begin reading out in the first half of 2023.”

The Company believes its drug delivery technology platform has the potential to be effective in EoE based on the proven efficacy of oral immediate release fluticasone propionate in this indication, and the growing library of data supporting the value of extended-release steroids in a variety of indications. The Company’s technology is underpinned by a novel polymer membrane designed to release drug at a pre-defined rate, which could result in an effective, sustained treatment for EoE, improving patient outcomes. ?

For more information, please view the press release here:

https://eupraxiapharma.com/news/default.aspx