Enhancing rabbit reproductive biotechnology with ABT’s IMAC resins

Revolutionize rabbit reproduction with Agarose Bead Technology. Our high-density nickel columns ensure pure and stable rrβ-NGF, enhancing sperm motility and ovulation induction

Advances in molecular biology and biochemistry have revolutionized the field of reproductive biotechnology. This study published in PLOS ONE, "Recombinant rabbit beta nerve growth factor production and its biological effects on sperm and ovulation in rabbits," highlights the potential of recombinant rabbit β-NGF (rrβ-NGF) in improving rabbit reproduction.?

This is where Agarose Bead Technology's products come into play, offering innovative solutions for the challenges faced in this field.?

Agarose Bead Technology specializes in the purification and handling of delicate biological compounds like rrβ-NGF.

Our high-density nickel columns provide a gentle yet effective medium for purifying rrβ-NGF produced in CHO cells, as described in the study.?

By using our technology, researchers can ensure higher purity and stability of rrβ-NGF, which is critical for its biological effectiveness. The study demonstrated that rrβ-NGF improved sperm motility without affecting its viability (Figure 1), and the the ovulation-inducing effect of rrβ-NGF when added to seminal doses in female rabbits.?

Attending to the results of this study, Agarose Bead Technology's IMAC products increase the purity and yield of rrβ-NGF.

Our commitment to advancing research and development in this field is firm, as we continue to offer innovative solutions that meet the evolving needs of scientists and researchers worldwide.

Get to know more about our affinity chromatography resins.

1. Sanchez-Rodriguez A, Abad P, Arias- Alvarez M, Rebollar PG, Bautista JM, Lorenzo PL, et al. (2019). Recombinant rabbit beta nerve growth factor production and its biological effects on sperm and ovulation in rabbits. PLoS ONE 14(7): e0219780.