Product Name: 25-Hydroxy Vitamin D?
HS Code: 2936290000
CAS NO: 63283-36-3
Advantages:
- Research Proven: Multiple studies have demonstrated that 25-OH-D? plays a crucial role in poultry farming. It ensures the health of poultry's intestines, bones, liver, and kidneys, while boosting their immunity and production performance.
For Laying Hens (Complete Laying Cycle):
- Improves Egg Production: Significantly increases egg production rate and extends the laying cycle.
- Bone Health: Reduces osteoporosis and cage layer fatigue.
- Egg Quality: Enhances eggshell strength and thickness, reducing the incidence of misshapen, thin-shelled, and broken eggs.
For Broilers:
- Growth: Increases weight gain and the yield of breast and leg meat.
- Bone Health: Reduces skeletal diseases and improves rickets.
- Immunity: Enhances immunity, thereby improving survival rates.
For Breeding Chickens:
- Egg Production: Significantly boosts egg production rate.
- Semen Quality: Improves the quality of rooster semen, increasing fertilization and hatch rates.
For Livestock (Pigs):
- Semen Quality: Effectively increases the volume and sperm count of boar semen.
- Fertility: Improves the conception rate of sows, thereby enhancing piglet survival rates.
- Health: Improves limb and hoof health, reducing the culling rate of breeding pigs.
Economic Benefits:
- Value Addition: Using 25-OH-D? significantly enhances the economic value of animals, bringing more economic benefits. According to our experiments, an investment of $1 can generate approximately $10 in value.
Cost and Quality Control:
- Cost-Effective: Full industry chain layout constructs a cost moat, with controlled quality and sources of raw materials.
- Technical Support: Provides comprehensive technical services, including formula expert guidance, dosage form customization, and support. Uses green chemical synthesis technology, which is environmentally friendly.
Q&A
Q: What environmental factors affect the storage of 25-OH-D? products? What are the storage precautions?
- Light and humidity have a significant impact on the product.
- Store in a dark place, below 25°C, and use as soon as possible after opening.
Q: Are there any interactions or effects of 25-OH-D? products with other vitamins, trace elements, or drugs?
- According to current patents, literature, and feed additive safety requirements, 25-OH-D? should not be added to feed simultaneously with VD2. Concurrent use can cause elevated blood calcium levels, leading to gastrointestinal and central nervous system diseases, soft tissue calcification, and even death.
- Calcifediol can be used concurrently with VD3 within certain limits and shows a synergistic effect according to data. (Data attached)
- There are no adverse reactions with other vitamins and trace elements, similar to VD3 effects.
Q: What are the side effects of 25-OH-D? compared to VD3?
- No side effects; instead, it has better absorption and bioavailability.
- Calcifediol is converted from vitamin D3 (VD3) in the liver by VD3 hydroxylase and mainly exists in the blood as calcifediol. It is further converted in the kidneys to 1,25-dihydroxy vitamin D3 (calcitriol), a hormone with 2-5 times the activity of calcifediol. Both promote the reabsorption of calcium in bones and the absorption of Ca2+ in the small intestine. Therefore, calcifediol better regulates calcium and phosphorus metabolism in the body, promoting calcium and phosphorus absorption in the small intestine, deposition in bone tissue, and bone formation.
Q: What is the dosage of 25-OH-D? in feed for laying hens at different growth stages?
- 5% before peak laying: 1.25%, 5g/ton
- 5% to peak: 3g/ton
- Post-peak to culling: 5g/ton
Q: How does 25-OH-D? enhance disease resistance in animals?
- Immune Modulation: Calcitriol (1,25(OH)2-VD3) promotes monocyte differentiation into macrophages, enhancing their chemotaxis and phagocytic functions. Studies from 2006 and 2007 showed that activation of TLR receptors on monocytes and macrophages upregulates VDR (vitamin D receptor) and downstream target genes. Antimicrobial peptides like cathelicidin and defensin b4, induced by the vitamin D signaling pathway, exhibit direct antimicrobial activity. Active vitamin D regulates innate immunity via NKT and NK cells. It modulates T cells, directly inhibiting the release of inflammatory cytokines, inducing Treg cells, and producing anti-inflammatory factors like IL-10. It directly inhibits B cell proliferation, differentiation, and immunoglobulin secretion, increases B cell apoptosis, and inhibits memory B cell production.
Q: How does 25-OH-D? enhance reproductive capacity in breeding animals and poultry?
- Pigs: Enhances sperm motility, semen volume, and sperm count; increases retention rates in gilts, reduces culling rates in breeding sows, improves piglet survival rates, and shortens farrowing duration.
- Poultry: Increases egg production rate, hatchability, and chick viability; reduces egg breakage and mortality rates; extends peak laying periods; and improves rooster semen quality and quantity.
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