Effect of neuronavigated repetitive transcranial magnetic stimulation on pain, cognition and cortical excitability in fibromyalgia syndrome

This randomized, double-blind, sham-controlled trial assessed the effects of repetitive transcranial magnetic stimulation (rTMS) on fibromyalgia patients. Thirty-four participants were randomized into active or sham groups, with the active group receiving 20 sessions of rTMS at 1 Hz. Active therapy significantly reduced pain intensity (P < 0.001) and improved cognition and sleep quality compared to sham treatment. The results suggest that rTMS is an effective tool for managing pain, cognitive issues, and sleep disturbances in fibromyalgia, potentially alleviating the condition's associated morbidity.

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