Edition 26: October 2024

Polaris Dawn Crew Uses Mitra Devices in Space

Scientists working with the civilian flight crew on the Polaris Dawn mission to space in September 2024 conducted a pharmacokinetic study using Neoteryx? Mitra? microsampling devices with VAMS? technology by Trajan Scientific and Medical. This finger-stick blood sampling study investigates how pharmaceuticals are metabolized by people traveling in space, where microgravity could alter drug efficacy, dosage requirements, or side effects. The blood samples collected inflight by the Polaris Dawn crew using the Mitra? devices are providing invaluable insights into these potential changes, helping to ensure the safe and effective use of medications for astronauts and civilians during future space flight.

For details about this study, please read our blog: Polaris Dawn Crew Uses Trajan's Microsampling Devices in Space (neoteryx.com)

Developing “Cutaneous Digital Twins” from Skin Biopsies

A new study paper published in the September issue of the Journal of Investigative Dermatology (jidonline.org), describes how punch biopsy, such as the Harpera? Microbiopsy Punch, can aid researchers in performing skin microsampling for the development of “cutaneous digital twins” from skin biopsies. The cutaneous digital twins could help advance molecular skin profiling and the development of computer skin models for studies in permeability and diffusion of topical drugs and cosmetics to personalize dermatology treatments.

A cutaneous digital twin would start with a microscopic skin sample collected from a study subject (patient) using Trajan’s Harpera Microbiopsy Punch. The Harpera punch is minimally invasive, offering virtually painless skin specimen collection. Currently in development and available for investigational use only (IUO), the Harpera is designed to enable a suture-free and scarless skin biopsy procedure that doesn't require a numbing agent or anesthesia.

For details about this study, please read our blog: Microbiopsy Punch May Aid Molecular Profiling in Dermatology (neoteryx.com)