Do you have a stomach ache?

Do you have a stomach ache?

High level Oxalic Acid causes Inflammatory Bowel Disease ?

Quantify with our LC-MS/MS Gut Microbiota Kit

?Oxalate, a compound produced by many edible plants and as a terminal metabolite in the liver of mammals, is a toxin that has a detrimental role to human health. Humans and other mammals do possess enzymatic systems to degrade oxalate. Moreover, numerous oxalate-degrading bacteria reside in the mammalian Gut and, thus, provide an important function for hosts.

Inflammatory bowel disease (IBD) is a term for two conditions (Crohn’s disease and ulcerative colitis) that are characterized by chronic inflammation of the gastrointestinal (GI) tract. Prolonged inflammation results in damage to the GI tract.

What are the common symptoms of IBD?

·?????? Persistent diarrhea

·?????? Abdominal pain

·?????? Rectal bleeding/bloody stools

·?????? Weight loss

·?????? Fatigue

Patients with IBD frequently suffer from disrupted oxalate homeostasis and calcium oxalate nephrolithiasis. We show that the enteric oxalate level is elevated in IBD patients, with highest levels in Crohn’s disease patients with both ileal and colonic involvement consistent with known nephrolithiasis risk.

You can learn the amount of Oxalic Acid level with the Zivak Gut Microbiota kit, by LC-MS/MS.

For detailed information: Zivak Gut Microbiota Dysbiosis Markers Urine LC-MS/MS analysis kit

Academic paper: Microbial genetic and transcriptional contributions to oxalate degradation by the gut microbiota in health and disease

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