Decision making in Parkinson's disease

Decision making in Parkinson's disease

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Decision-making difficulties may arise in Parkinson's disease (PD), particularly due to a propensity toward rewarding but riskier options. A popular tool for examining decision-making processes involving these possibilities is the Iowa Gambling Task. The job evaluates risk management and feedback-gathering skills. Along with the classic motor symptoms, cognitive abnormalities are present in a large proportion of people with Parkinson's disease (PD). These deficiencies mainly affect executive processes, which are most likely related to prefrontal dysfunctions brought on by a reduction in dopaminergic transmission in fronto-striatal loops. We used a neuropsychological test battery and the Game of Dice Task to study 20 non-demented PD patients and 20 healthy control subjects in order to look into potential relationships between decision-making and executive processes in PD. The conventional wisdom holds that the basal ganglia are solely motor structures that are crucial for movement selection and execution. Because of the close connection between the frontal cortex's executive function areas and the basal ganglia, their significance in cognitive functioning has just lately come to light. It has been demonstrated that dopaminergic medications are useful in reducing a number of the motor symptoms linked to Parkinson's disease. On the other hand, its impact on cognitive function can vary, sometimes improving and other times making performance on particular tests worse.

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