December Epigenetics Newsletter

December Epigenetics Newsletter

Active Motif has teamed up with?EpiGenie?to deliver you the best collection of recent epigenetics news articles and educational resources to ensure that you can stay on top of what’s new in epigenetics research.

Can Engineering Chromodomains Take Histone Methylation to “Affinity” and Beyond!?

The troupe of “toys” we use to explore the world of histone methylation just gained a new friend thanks to a playful team of epigenetic engineers who have taken histone modification-reading chromodomains to “affinity” and beyond! Read More >>??

EpiGenie eBook: Epigenetics and DNA Methylation

One of the longest-known and most studied epigenetic markers is DNA methylation, which can regulate gene expression and genomic organization in nearly all organisms. Here we take a look at some particularly interesting publications on both the epigenetic mechanisms and new methods being applied to this exciting field. Read More >>

[BLOG POST] DNA Methylation for Predicting Prostate Cancer: Where Do We Stand?

Some say that Epigenetics touches everything. The marriage between DNA methylation, one of the earliest and most studied of epigenetic mechanisms, and its potential to be a powerful biomarker for disease is exciting and promising. In this overview, we look at prostate cancer research in particular - where we stand in this regard, and also a “new” biomarker associated with voltage-dependent calcium channels! Read More >>

[BLOG POST] The Bugs in the Bees Impact Epigenetic Mechanisms to Keep Things Social

Symbiotic interactions between animal hosts and their gut microbiota can include bacteria, archaea, fungi, and viruses all living in the digestive tract. Some can even modulate the function of the nervous system in a way tha can impact social behavior – normal and dysfunctional. We take a look at some cool work done, using honeybees as a model, that explores this connection between epigenetics, the brain, and behavior. Read More >>

[BLOG POST] Mass Spectrometry – Attaining Massive Amounts of Histone Modification Data from Small Clinical Samples

A new advance now permits the profiling of histone modifications from vanishingly small amounts of clinical samples via mass spectrometry. The ability to profile histone modification levels in tumor subpopulations may permit the field to make massive strides forward in our understanding of tumor metastasis, intratumor heterogeneity, therapeutic responses by tumors, and the role of tumor subpopulation interactions in driving tumorigenesis and identifying potentially useful biomarkers. Read More >>

[PODCAST] Genome Organization Mediated by RNA Polymerase II with Argyrys Papantonis

In this episode of the Epigenetics Podcast, we caught up with Akis Papantonis from the University Medical Center G?ttingen to talk about his work on genome organization mediated by RNA Polymerase II. Listen Now >>

[PODCAST] The Role of Pioneer Factors and Grainyhead at the Maternal-to-Zygotic Transition

In this episode of the Epigenetics Podcast, we caught up with Melissa Harrison from the University of Wisconsin-Madison to talk about her work on the “Pioneer” Transcription Factors - Zelda and Grainyhead - and their role at the maternal-to-zygotic transition. Listen Now >>

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