Debris Mask Your True Results

New single-cell technologies have recently facilitated deeper exploration of inter- and intratumor heterogeneity than previously possible. These innovations are poised to better inform on underlying molecular and cellular characteristics that impact key disease mechanisms such as drug resistance and tumor recurrence.

Before any downstream analyses, especially with regards to tumor microenvironment monitoring, cells need to be processed into suspensions that are free of debris and aggregates. Current workflows often fall short of reliably yielding the desired cell types at a high frequency, thereby hampering accurate measurements of tumor-infiltrating leukocytes, including rare immune subsets. Pre-analytical factors have long been neglected when interpreting flow cytometry fit-for-purpose results.

However, preserving original cell biology and eliminating interfering debris as much as possible across applications is crucial to overall data quality and reproducibility. It can be achieved by adopting automation solutions such as Curiox's Laminar Wash Technology to ensure better, standardized sample preparation for fluorescence-based assays.

Could Debris Be Masking Your True Results: A Scientist’s Perspective on The Importance of Sample Prep

Curiox in partnership with Genome Web, will host an interesting webinar with key opinion leader from Charles River Laboratories, Christoph S. Eberle, to discuss how Laminar Wash technology improves data recovery; it is on Monday, June 20, 2022.

Overview and Register here ??????