DCEG at AACR Annual Meeting: April 5-9, 2024

Each year, DCEG scientists present their research at the American Association for Cancer Research (AACR) Annual Meeting. The 2024 meeting will be held at the San Diego Convention Center in San Diego, California, from April 5 - 10.

See below for the DCEG-led workshops, presentations, and posters.?Our scientists would love to speak with you, so please say hello!

The?full program?can be found on the AACR Website .

Saturday, April 6

Workshops

Existing and Emerging Cohort Study Resources for Future Discoveries?

8:00 AM - 9:30 AM PDT, Room 11 - Upper Level

Mia Gaudet: Connect for Cancer Prevention Study: An emerging cohort

Analytic Resources and Applications for AACR Project GENIE BPC Clinico-genomic Data

8:00 AM - 9:30 AM PDT, Room 28 - Upper Level?

Bin Zhu: Pan-cancer mutational signature analysis of 111,711 targeted sequenced tumors using SATS

Sunday, April 7

Presentation

Population Sciences Working Group Meeting

6:00 PM - 8:00 PM PDT, Sapphire Ballroom – Hilton Bayfront Hotel

Nicolas Wentzensen: Connect:?A new cohort to study cancer causes and prevention

Posters

Environmental and Occupational Risk Factors, Infection, and Aging

1:30 PM - 5:00 PM PDT, Section 34

Vicky Chang : Farm animal exposures and the oral microbiome in the Agricultural Health Study

Patricia Erickson, MPH, PhD : Carbaryl use and cancer incidence in the Agricultural Health Study - an updated analysis

Jongeun Rhee, ScD, MS : Serum concentrations of per- and polyfluorinated substances and risk of non-Hodgkin lymphoma

Deborah Tadesse : Interaction between solvent exposure and genetic susceptibility and risk for bladder cancer

Jason Tribble: The burden of Merkel cell carcinoma attributable to immunosuppression, ultraviolet radiation, and Merkel cell polyomavirus in the United States

Cancer Disparities 1: Emerging Trends in Cancer Disparities Research

1:30 PM - 5:00 PM PDT, Section 33

Wayne Lawrence : Severe housing cost burden and premature cancer mortality by state Medicaid expansion status

Prevention/Early Detection Interception: Epidemiology

1:30 PM - 5:00 PM PDT, Section 32

Lisa Mirabello : Underlying germline genetic architecture of pediatric sarcomas: Evaluating the role of common and rare variants in 4,160 patients

Charles Rabkin: GrafGen: Distance-Based Inference of Population Ancestry for Helicobacter pylori Genomes

Monday, April 8

Nicolas Wentzensen will deliver a "Meet the Experts" session on the?Connect for Cancer Prevention Study ?at the NCI Exhibit Booth?from?9:30 AM - 10:30 AM PDT.

Jackie A. Lavigne, PhD, MPH will be at the NCI Exhibit Booth from?11:00 AM - 1:00 PM PDT?to talk about?fellowships in DCEG .?

DCEG Staff and Alumni Social Gathering,?5:30 PM - 6:30 PM PDT?at the?Hilton San Diego Bayfront Odysea Bar.

Presentation

Cancer Disparities Research

2:30 PM - 4:30 PM PDT, Room 14 - Mezzanine Level?

Aimee Koestler : HPV45 and HPV52 prevalence, within‐type variants, and precancer/cancer risks differ by race/ethnicity

Posters

Liquid Biopsy and Precision Oncology

9:00 AM - 12:30 PM PDT, Section 36

Jazmyn Bess : Impact of delayed processing on cfDNA quantity and Qqality using STRECK cfDNA tubes: Connect pilot study

Cell Cycle, DNA Repair, and Telomere Biology

9:00 AM - 12:30 PM PDT, Section 13

Michelle Ho : Exploring the role of a TERT intronic tandem repeat in regulating cell proliferative responses to environmental factors and cancer risk

Diet, Alcohol, Tobacco Use, and Other Lifestyle Risk Factors

9:00 AM - 12:30 PM PDT, Section 33

Mitchell Machiela : Modifiable risk factors are associated with clonal hematopoiesis

Role of Diet, Nutrition, and the Microbiome Across the Cancer Continuum

9:00 AM - 12:30 PM PDT, Section 33

Semi Zouiouich: Sample size estimations based on human microbiome temporal stability over six months: A shallow shotgun metagenome sequencing analysis

Risk Prediction Modeling, Screening, Early Detection, and Preneoplastic and Tumor Markers

1:30 PM - 5:00 PM PDT, Section 33

Thomas Ahearn: Development and prospective validation of an estrogen receptor positive breast cancer risk model to identify women who could benefit for risk-reducing therapies

Population Sciences: Biomarkers of Endogenous or Exogenous Exposures, Early Detection, Biologic Effects, and Prognosis

1:30 PM - 5:00 PM PDT, Section 32

Demetrius Albanes : Blood metabolomic profile of glioma risk: A pooled, multi-cohort analysis in COMETS

Kara Barnao : Characterization of co-occurring clonal hematopoiesis to identify high risk clones associated with hematologic cancer risk

Somayina Ezennia, MPH CPH : Associations Between Estimated Endotoxin Exposure and Circulating Immunological Markers Among Male Farmers

Biomarkers of Endogenous or Exogenous Exposures, Early Detection, Biologic Effects, and Prognosis

1:30 PM - 5:00 PM PDT, Section 32

Rebecca Kelly : Mosaic loss of the Y chromosome is associated with prostate cancer risk

Late-Breaking Research: Molecular/Cellular Biology and Genetics 1

1:30 PM - 5:00 PM PDT, Section 53

Gulzar Daya : Methylation subtypes of skull base chordoma

Late-Breaking Research: Tumor Biology 1

1:30 PM - 5:00 PM PDT, Section 54

Tongwu Zhang : Deciphering lung adenocarcinoma evolution and the role of LINE-1 retrotransposition

Tuesday, April 9

Mia Gaudet ? will deliver a "Meet the Experts" session on the?Connect for Cancer Prevention Study ?at the NCI Exhibit Booth from?11:00 AM - 11:30 AM PDT.

Jackie A. Lavigne, PhD, MPH will be at the NCI Exhibit Booth from?3:00 PM - 5:00 PM PDT?to talk about?fellowships in DCEG .?

Posters

Cancer Disparities 2: Survivorship Research Addressing Cancer Disparities

9:00 AM - 12:30 PM PDT, Section 33

Yingxi (Cimo) Chen : Patterns and predictors of opioid dispensing among older cancer patients from 2008 to 2015

Characterization of Mutational Processes and Drivers in Cancer Development and Evolution

9:00 AM - 12:30 PM PDT, Section 15

Isabel Rodriguez Sanchez : Insight into the structure of breakage fusion bridge events and chromothripsis in cancer cell lines using long-read sequencing

Sonm Tulsyan : A high rate of episomal HPV 16 is present in head and neck squamous cell carcinoma tumors by long-read whole genome sequencing

Late-Breaking Research: Bioinformatics, Computational Biology, Systems Biology, and Convergent Science 2

9:00 AM - 12:30 PM PDT, Section 51

Monjoy Saha : Deep learning-based molecular characterization of lung cancers from never smokers using hematoxylin and eosin-stained whole slide images

Population Sciences/Genetic Epidemiology 1: GxE, GWAS, and Next-Generation Sequencing

1:30 - 5:00 PM PDT, Section 33

Batel Blechter, PhD, MA : Polygenic risk score and lung adenocarcinoma risk among never-smokers by EGFR mutation status

Wen-Yi?Huang: Relationship between polygenic risk score, lifestyle factors, and colorectal cancer risk

Aubrey K. H. : Multiple new Ewing sarcoma susceptibility loci expand knowledge of germline genetic etiology and nominate mechanisms of risk

Timothy Winter : Targeted CRISPRi screen identifies functional variants and novel target genes at multiple renal cell carcinoma (RCC) susceptibility loci

Shahriar Zamani : Germline variants in cancer susceptibility genes and subsequent neoplasm risks after childhood cancer: A pooled analysis of two large-scale cohorts

Cancer Disparities 3: Using Molecular Epidemiological Approaches to Decipher Cancer Disparities

1:30 - 5:00 PM PDT, Section 32

Alexandra Harris : Investigation of breast tumor biology and microenvironment in women of African descent using a single cell multiomic approach

Population Sciences

1:30 - 5:00 PM PDT, Section 33

Shisi (Lydia) He : Genome-wide association study identifies new genetic susceptibility loci For multiple primary cancers

Genomic Changes and Intratumoral Heterogeneity as Predictive Biomarkers for Clinical Outcome

1:30 - 5:00 PM PDT, Section 53

Azhar Khandekar : Extrachromosomal DNA in lung cancer from never smokers

Genomic Changes and Intratumoral Heterogeneity as Predictive Biomarkers for Clinical Outcome

1:30 - 5:00 PM PDT, Section 16

Wei Zhao : Transcriptomic profiling of lung adenocarcinoma from never-smokers reveals molecular subtypes with clinical implications

Wednesday, April 10

Posters

Genetic Epidemiology 2: Family Studies, Pathway Analysis, and Functional Genetics

9:00 AM - 12:30 PM PDT, Section 31

Alex Kane : Investigating the cell-type specific regulation of IRF4 and its role in lung cancer via a lung cancer risk-associated pleiotropic variant

Modifications and Signaling to Cancer Drivers

9:00 AM - 12:30 PM PDT, Section 18

Brenen Papenberg: Epidemiology meets epitranscriptomics: Exploring the cancer-related role of a novel? TERT -antisense transcript and its regulation by RNA methylation