Data Dose October 2024 #2
Dispensing Errors and How to Prevent Medication Safety Risks
Medication safety is crucial for achieving optimal health outcomes. With the global increase in prescription volumes, recognizing and preventing dispensing errors has become more important than ever. These errors pose a serious threat to patient safety and can lead to unwanted, sometimes severe, adverse events. In many cases, such errors result in hospitalization, long-term health complications, or even death. Read more...
Researchers Discover Aspirin’s Surprising Ability To Combat Hormonal Deficiency
Researchers at the Francis Crick Institute have shown that gut bacteria balance can influence hypopituitarism symptoms in mice, a condition caused by mutations in the Sox3 gene, which also affects humans by leading to hormone deficiencies in the pituitary gland. In people, this can result in growth problems, infertility, and poor stress responses. In a study published in PLOS Genetics, the team removed Sox3 from mice, leading to hypopituitarism, and found that the gene primarily affects the hypothalamus. Additionally, they discovered that aspirin could help alleviate hormone deficiency symptoms in the mice. Read more...
领英推荐
Researchers use AI to find non-opioid pain relief options
Around one in five Americans suffer from chronic pain, with current treatments often falling short. Feixiong Cheng, Ph.D., Director of Cleveland Clinic's Genome Center, and IBM are leveraging artificial intelligence (AI) to enhance drug discovery for advanced pain management. Their deep-learning framework identified several gut microbiome-derived metabolites and FDA-approved drugs that could be repurposed as non-addictive, non-opioid treatments for chronic pain. Read more...
Pseudoephedrine at a Crossroad: Relief or Risk?
Pseudoephedrine, a common ingredient in over-the-counter decongestants, has long been a popular choice for treating cold and flu symptoms due to its effectiveness in relieving nasal congestion. However, recent safety concerns have raised awareness about its potential link to serious conditions like Posterior Reversible Encephalopathy Syndrome (PRES) and Reversible Cerebral Vasoconstriction Syndrome (RCVS). For pharmacovigilance specialists, these concerns highlight the importance of monitoring, reporting, and ensuring adequate safety measures for this widely used drug. Read more...