Cyclodextrins in Cosmetics: The Hidden Ingredient Boosting Your Skincare
source: https://chemicalsinourlife.echa.europa.eu/chemicals-in-cosmetics

Cyclodextrins in Cosmetics: The Hidden Ingredient Boosting Your Skincare

This week we will touch the role of cyclodextrins in the cosmetic industry.


Have you ever heard of cyclodextrins? These little molecules may not be household names, but they are quietly revolutionizing the world of cosmetics.

Cyclodextrins are cyclic oligosaccharides that are commonly used as solubilizing agents in pharmaceuticals and food products. In recent years, they have also become popular in the cosmetics industry due to their unique ability to enhance the effectiveness of skincare products.

So, how do cyclodextrins work in cosmetics? First, they have a hydrophobic interior and a hydrophilic exterior, which allows them to encapsulate hydrophobic ingredients such as vitamins, antioxidants, and essential oils. This encapsulation protects the ingredients from oxidation and degradation, which can reduce their effectiveness in skincare products.

Second, cyclodextrins can improve the stability and solubility of hydrophobic ingredients, making them easier to incorporate into skincare formulations. This can lead to more consistent and effective products that deliver visible results.

Cyclodextrins are also safe and biocompatible, making them an ideal ingredient for skincare products. They are non-toxic, non-irritating, and do not cause allergic reactions. They are also biodegradable and do not accumulate in the environment.

So, where can you find cyclodextrins in cosmetics? They are often used in serums, creams, and lotions that contain active ingredients such as retinol, vitamin C, and essential oils. They can also be found in hair care products that contain plant extracts and natural oils.


Why use cyclodextrins in cosmetics??

CDs as solubilizing agents

Stable aqueous solutions of insoluble compounds can be prepared without the use of organic co-solvents or surfactants and the rate of dissolution can be enhanced.

Flavor and odor coverage by encapsulation

CDs may be useful in covering the unfavorable organoleptic characteristics of some cosmetic products due to the presence of a particular active.

Liquid or oily materials can be transformed into powder forms

Some active ingredients in cosmetic preparations, such as α-tocopherol and vitamin A, occur in oily form and thus are difficult to handle. This problem can be easily solved by preparing a CD inclusion complex in solid state.

Controlled/extended release of fragrances?

CDs can be used to complex different fragrances, included in personal care products such as shampoos, deodorants, detergents and absorbent powders such as bath- and baby-powder products.

Protecting agents against light, heat, and oxidation?

CDs can increase the physical and chemical stability of guest molecules by protecting them against oxidation, decomposition, hydrolysis or loss by evaporation.

Preventing skin irritation?

The CDs alleviate local irritation and reduce side effects. CDs have advantages over other conventional penetration enhancers, such as fatty acids and surfactants.

Stabilization of emulsions and suspensions?

Incompatible compounds can be mixed and used together in complexed form.


Here are a few examples of cosmetic products and applications that contain cyclodextrins:

  1. Vitamin C serums: Cyclodextrins are often used to stabilize and solubilize vitamin C in serums, which helps to improve its effectiveness in brightening and evening out the skin tone.
  2. Retinol creams: Cyclodextrins can help to protect retinol from degradation and improve its stability, which can lead to better anti-aging results in creams and lotions.
  3. Essential oil hair treatments: Cyclodextrins can be used to encapsulate essential oils in hair treatments, which can help to protect the oils from oxidation and improve their efficacy in nourishing and strengthening the hair.
  4. Natural extract moisturizers: Cyclodextrins can be used to solubilize and stabilize natural plant extracts in moisturizers, which can help to enhance their moisturizing and antioxidant properties.
  5. Sunscreen formulations: Cyclodextrins can be used in sunscreen formulations to encapsulate UV filters, which can help to improve their stability and reduce skin irritation.

These are just a few examples, but there are many other cosmetic products and applications that can benefit from the use of cyclodextrins.


In summary, cyclodextrins may not be a well-known ingredient in cosmetics, but they are certainly a valuable one. They offer a range of benefits, from improving the stability and solubility of active ingredients to protecting them from degradation. So next time you shop for skincare products, look out for cyclodextrins on the ingredient list and know that you are getting a little extra boost for your skin.


Would you like to learn more? Here are some great sources to start with!

I would be delighted to hear suggestions for upcoming topics and engage in Q&A, so please feel free to add your impressions in comments or via email [email protected]. Thank you.


Next week we will continue exploring industrial applications one-by-one over the course of several editions. Household industry as promised! Stay tuned!

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