CRS Annual Meeting & Exhibition (21-23 July 2019, Valencia, Spain)

CRS Annual Meeting & Exhibition (21-23 July 2019, Valencia, Spain)


The CRS Conference just finished. And I would like to share the posters that my colleagues presented to update you with our recent research progress. 

Coating of small particles in the fluid-bed with aqueous-based polymer coatings is a challenging task which is coupling with problems of particles agglomeration and reducing the coating yield. So, on the first poster, you can see how this problem was successfully solved using the new technological approach supported with some insights with powder rheology investigation. 

No alt text provided for this image

The following video is representing used in this poster non-standard method of powder rheology investigation. This method was developed by us and wasn't described in literature before (at least we haven't found any information). Standard GranuDrum-device (drum rheometer) was utilised with additional external air-heater to maintain desirable powder temperature during the test.  

The second poster is representing the additional advantages of the technological approach (see the first poster) which allows not only to enable of small particles coating and highly increase the coating yield but also to reduce the amount of coating polymer amount to achieve the same result. 

No alt text provided for this image

And the third poster is introducing to the innovation of enteric-coated products dissolution testing. The advantage of this approach is concluded in the ability of the reliable method to provide bio-relevant dissolution test results. 

No alt text provided for this image
No alt text provided for this image

#SolidDosageForms #microparticles #particle #coatings #fluidbedcoating #Suspensions #multidose #formulation #controlledrelease #drugrelease #drugdelivery #drugdevelopment #excipients #pharmaceutical #UniversityOfHertfordshire #dissolution


Shrinivas Potukuchi

Vice President (BD) at Nimbasia Pharmaceuticals & Specialties India We manufacture Pharmaceutical/Nutraceutical grade Excipients (Powder and Granules form)

5 年

Nice,did you used Sudeep pharma magnesium stearate?

回复

要查看或添加评论,请登录

社区洞察

其他会员也浏览了