The Conundrum of Artificial Intelligence
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The Conundrum of Artificial Intelligence

Lessons learned from human genetic engineering and cloning?

Introduction:

As a physician. entrepreneur, technology enthusiast, and innovator, it is hard not to draw the similarities between two groundbreaking scientific developments and discoveries of our times, namely human genetic engineering, and the recent breakthroughs in artificial intelligence and in particular the rapid advancement in applications of generative large language models. These are two different areas of scientific breakthroughs, but a closer look at how society dealt with the ethical concerns and challenges surrounding human genetic engineering and cloning might provide some insights and guidance on how to handle similar issues raised by the highly disruptive applications of artificial intelligence in today's world.?

Human genetic engineering and cloning:

Human genetic engineering involves manipulating the DNA of an individual to change or enhance certain traits. This can be done through techniques such as CRISPR-Cas9, which allows scientists to make precise edits to the genome. Some potential applications of genetic engineering include treating genetic diseases and disorders, improving crop yields, and developing new medicines.?

However, genetic engineering also raises ethical concerns. One major issue is the potential for "designer babies," where parents could choose certain traits for their children such as eye color or intelligence. This raises questions about the societal implications of creating a class of genetically enhanced individuals and could potentially exacerbate existing inequalities.?

Cloning, on the other hand, involves creating an identical copy of an organism. In the case of human cloning, this could be used to create a duplicate of a particular individual. Some potential applications of human cloning include treating infertility, creating organs for transplant, and studying genetic diseases.?

However, like genetic engineering, cloning raises several ethical concerns. One major issue is the potential for abuse, such as creating clones for organ harvesting or military purposes. Additionally, cloning raises questions about the uniqueness and individuality of human beings, and whether creating exact copies of individuals undermines the value of human life.?

Overall, human genetic engineering and cloning are complex issues with both potential benefits and significant ethical concerns. It will be important for society to carefully consider the potential implications of these technologies as they continue to advance.?

Artificial intelligence and Generative Large Language Models:?

Artificial Intelligence (AI) refers to the ability of machines to perform tasks that would normally require human intelligence, such as learning, reasoning, problem-solving, and decision-making. Generative Large Language Transformer Models are a type of AI model that can generate natural language text based on a given prompt or input.??ChatGPT is a highly intelligent AI-powered bot which can learn complex queries and answer them quickly.

Benefits of generative large language models::?

  • Auto-regressive transformer models, such as GPT-3, can generate human-like responses to prompts, allowing for more natural and engaging conversations with machines.?
  • These models can learn from vast amounts of text data, enabling them to understand and generate more complex language and ideas.?
  • They can be fine-tuned for specific tasks, allowing for more accurate and efficient NLP applications.?
  • They can assist humans in tasks such as writing, translation, and summarization, potentially increasing productivity, and efficiency.?
  • They can enhance accessibility for individuals with disabilities, such as those who are visually impaired or have difficulty typing.?

Similarities of ethical concerns:?

There are some similarities between the ethical concerns of human genetic engineering and cloning and the application of artificial intelligence (AI) in human society. Here are some examples:?

  1. Bias and Discrimination: Both human genetic engineering and AI can perpetuate existing biases and discrimination. In the case of genetic engineering and cloning, there is a risk of creating genetic classes of people that are superior or inferior, while in AI, machine learning algorithms can amplify biases present in the data used to train them.?
  2. Control and Autonomy: Both human genetic engineering and AI raise concerns about control and autonomy. In the case of genetic engineering and cloning, there are ethical concerns about the control of human reproduction and the potential for creating individuals with predetermined traits. In the case of AI, there is a risk of loss of control and autonomy if machines become too intelligent and autonomous.?
  3. Safety and Security: Both human genetic engineering and AI raise concerns about safety and security. In the case of genetic engineering and cloning, there are concerns about the safety of manipulating the human genome, and the potential for creating unintended consequences and unforeseen harm. In the case of AI, there are concerns about the security of data and systems, and the potential for AI to be used for malicious purposes.?
  4. Responsibility and Accountability: Both human genetic engineering and AI raise concerns about responsibility and accountability. In the case of genetic engineering and cloning, there are ethical concerns about the responsibility for creating and using these technologies and the accountability for their consequences. In the case of AI, there are concerns about the responsibility for the actions of autonomous systems and the accountability for any harm caused by their use.?

Overall, these similarities highlight the need for careful consideration of the ethical implications of both human genetic engineering and AI, and the need for responsible and ethical development and use of these technologies in human society.?

Laws and legislation regarding human genetic engineering at both the international and national levels.?

Yes, there are several landmark laws and legislation regarding human genetic engineering at both the international and national levels. Here are some examples:?

International Laws and Agreements:?

  • Universal Declaration on the Human Genome and Human Rights (1997): This United Nations declaration outlines principles for the responsible use of genetic engineering, including respect for human dignity, privacy, and non-discrimination.?
  • Convention on Human Rights and Biomedicine (1997): This Council of Europe convention establishes guidelines for the use of genetic engineering in medicine, research, and reproduction, including informed consent and non-discrimination.?
  • International Declaration on Human Genetic Data (2003): This UNESCO declaration outlines principles for the collection, use, and storage of human genetic data, including informed consent, privacy, and non-discrimination.?
  • Nagoya Protocol on Access to Genetic Resources and the Fair and Equitable Sharing of Benefits Arising from their Utilization (2010): This United Nations agreement establishes guidelines for access to and use of genetic resources, including sharing of benefits and protection of traditional knowledge.?

United States Enacted Laws and Legislation:?

  • Genetic Information Nondiscrimination Act (GINA) (2008): This federal law prohibits discrimination based on genetic information in employment and health insurance.?
  • The National Institutes of Health (NIH) Guidelines for Human Stem Cell Research (2009): These guidelines establish ethical principles and guidelines for the use of stem cells in research, including informed consent and minimizing harm to embryos.?
  • New York State’s 2019 Reproductive Health Act: This legislation legalizes abortion in New York and allows for the use of genetic engineering techniques in reproductive medicine.?

These laws and agreements reflect ongoing debates about the ethical and legal implications of human genetic engineering, as well as the need for international cooperation and standards in this field.?

Ethical Considerations for implementing artificial intelligence

The provisions of the UNESCO recommendations regarding the ethical regulation of artificial intelligence:?

  1. Inclusiveness and participation: Ensure that the development of AI systems involves diverse perspectives, including those of marginalized and underrepresented communities.?
  2. Human-centered values and democratic participation: Ensure that AI systems are designed to respect human dignity, privacy, and autonomy and that their development is guided by democratic values and principles.?
  3. Transparency and explainability: Ensure that AI systems are transparent and explainable so that users can understand how they work and how decisions are made.?
  4. Fairness and non-discrimination: Ensure that AI systems are designed and used in ways that are fair and non-discriminatory and that they do not perpetuate or amplify biases.?
  5. Responsibility and accountability: Ensure that AI systems are developed and used in ways that are responsible and accountable and that there are mechanisms in place to address and redress any harm caused by their use.?
  6. Safety and security: Ensure that AI systems are designed and used in ways that are safe and secure and that they are not used for malicious purposes.?
  7. Sustainability: Ensure that the development and use of AI systems are sustainable and that their environmental and social impacts are considered.?

Overall, these recommendations reflect a growing recognition of the need for ethical and responsible development and use of AI systems, and the need to ensure that these technologies are aligned with human values and principles.?

The similarities between these two scientific endeavors to improve the human condition and make the world a better place cannot be denied. Although differences exist in the two circumstances, we can look to the lessons learned from the debate around human genetic engineering and cloning to provide guidance on how ethics should be integrated into the development of AI.?The ethical implications of creating artificial intelligence must be taken seriously, as there is potential for great harm to arise if certain safeguards are not put in place. There should be transparency, accountability and meaningful oversight from both industry and government regulators, who have a responsibility to ensure that ethical boundaries are not crossed during the development of AI.?The use of AI should also be done in a manner that respects human autonomy and upholds the value of individual privacy.

Disclaimer: Generative AI was used to provide some of the contents of this blog/article - The author has done his best to check the facts contained here in. Should you find any factual errors, please do not hesitate to provide your comments below or send to [email protected].

Jordan Wahbeh

VC, Syndicate VC - Talks about #Investor, #VentureCaptial, #Startups, #Operations, #BizDevelopment, #syndicates , #Doinggood

1 年

will these factors be less or more concerning than the human ones - "...including bias and discrimination, control and autonomy, safety and security, and responsibility and accountability..." Will it be more consistent, or less visible!! A few weeks back, City of San Francisco "limited RoboTaxis" because one car "blocked traffic". I wonder how often does a "human driven" car block traffic!

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Amos Dare MD, FACS

Neurosurgeon, Founder - MedMatch Network | Digital Health Transformation Leader | Artificial Intelligence and Healthcare | Patient Advocacy | Author

1 年

Thank you

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