The Connection Between Skin Conditions and Mental Health

The pursuit of "perfect skin" has become a widespread phenomenon. Many individuals invest heavily in different skincare products, such as serums, acne patches, and concealers, to hide perceived flaws. This obsession with skin appearance isn't merely cosmetic; research demonstrates a strong correlation between skin condition, mental health, and overall quality of life. This intense chase for flawless skin often leads to people struggling with anxiety and depression, as they live with a constant sense of failure to meet these unrealistic and often unattainable standards.

The Impact of Skin Conditions on Emotional Well-being

Skin inflammatory diseases like acne, atopic dermatitis, and psoriasis can significantly impact mental health. Studies reveal that these conditions are linked to increased anxiety, depression, low self-esteem, and even suicidal attempts. But the most common mental health disorder diagnosed in acne patients was social phobia. Model Kendall Jenner has openly shared how acne affected her self-esteem, saying,

"I wouldn't look people in the eye. Acne just killed my self-esteem. I thought when I didn't look at someone, they couldn't see my face."?

In a study of almost 5000 18-19 year-olds, teenagers with substantial acne reported having “low attachment to friends”, “not thriving at school”, and ”never having had a romantic relationship or sexual intercourse” significantly more often than their peers who did not struggle with acne.?

Psoriasis patients also perceive themselves as subjects of stigmatization, which was especially emphasized in patients under 30 years old. They often admitted the fear of rejection or being flawed. In an Italian study, 62% of all patients with psoriasis, especially those with lower education levels, had some depressive disorder symptoms.

The Molecular Link Between Skin Inflammation and Mental Health

On a molecular level, skin inflammatory diseases affect mental health by triggering a complex cascade of hormones and neurotransmitters (chemical messengers in the body). Certain chemicals in our body (pro-inflammatory cytokines and chemokines) can cause redness, swelling, and irritation in specific areas of the skin but can also enter the bloodstream. This is when they can alter serotonin and dopamine pathways (brain chemicals that affect mood) and affect key part of the body’s stress response system. Stress about our skin's appearance can only further worsen these conditions, creating a vicious cycle of psychological distress and skin problems. The stress and chronic inflammation increase cortisol production (a stress hormone), which could lead to anxiety and depression.

On top of that, neuropeptides, contribute to pain and itch sensations. Sleep disturbances due to this itchiness and pain can further worsen mental health issues. Picking the blemishes is recognized as one of the anxiety-coping mechanisms, which is also affecting the skin negatively, as it can lead to scarring. Chronic skin inflammation can also affect the brain by making it easier for harmful substances to enter and disrupt the function of nerve cells.

The Psychological Footprint of Aging?

Inflammation plays a huge role in the biology of aging. As time passes, our bodies are increasingly exposed to UV radiation or pollution while internally the hallmarks of aging contribute to the skin losing elasticity and tone evenness. However, the relationship between lines, wrinkles, and mental health is more intricate than that of skin pathologies like acne or psoriasis. While acne and psoriasis are often associated with more immediate and acute psychological distress, the slow progression of wrinkles and lines can lead to a different, more pervasive type of emotional response which is further increased by societal attitudes toward aging and beauty.??

Research indicates that women, in particular, may experience a decline in self-esteem and confidence as visible signs of aging become more pronounced. A case study found that women who were dissatisfied with their facial appearance, including the presence of wrinkles, experienced higher levels of anxiety and social withdrawal.

Recently, media campaigns advocating for "loving your wrinkles" have become widely popular, promoting the idea that wrinkles can be seen as a natural and beautiful part of aging. These campaigns aim to shift the perception of wrinkles from a negative to a positive attribute, encouraging individuals to embrace their aging skin with confidence. However, despite the widespread appeal of these campaigns, whether reframing wrinkles as a confidence-boosting feature is truly effective has not been thoroughly measured or published in peer-reviewed journals yet. The lack of empirical data on this subject leaves a gap in understanding the potential psychological benefits of such a mindset shift, highlighting the need for further research in this area.

Power of Beauty Brands in Mental Health Improvement

Using inappropriate cosmetics can exacerbate skin conditions and mental health issues. Beauty brands have the power and potential to play a significant role in addressing these problems. Considering that professional health care is often hard to access, many people rely on brand claims and general research for their skincare solutions. This is where skincare brands can make a substantial impact by offering personalized product recommendations that address individuals' unique skin concerns.

For instance, skin analysis technologies on brand websites can accurately assess skin conditions and recommend suitable products with high precision, thus reducing the trial-and-error phase that many individuals experience. Successful management of skin conditions through effective products leads to long-term customer loyalty and positive word-of-mouth, benefiting both parties immensely.

References:

1. Nagae M, Mitsutake T, Sakamoto M. Impact of skin care on body image of aging people: A quasi-randomized pilot trial. Heliyon. 2023;9(2):e13230. Published 2023 Jan 27. doi:10.1016/j.heliyon.2023.e13230
2. Steven Dayan, Steven G Yoelin, Koenraad De Boulle, Julie K Garcia, The Psychological Impacts of Upper Facial Lines: A Qualitative, Patient-Centered Study, Aesthetic Surgery Journal Open Forum, Volume 1, Issue 2, June 2019, ojz015, https://doi.org/10.1093/asjof/ojz015
3. Cortés H, Rojas-Márquez M, Del Prado-Audelo ML, Reyes-Hernández OD, González-Del Carmen M, Leyva-Gómez G. Alterations in mental health and quality of life in patients with skin disorders: a narrative review. Int J Dermatol. 2022;61(7):783-791. doi:10.1111/ijd.15852.
4. Wang, Y. N., Fang, H., & Zhu, W. F. (2009). Survey on skin aging status and related influential factors in Southeast China. Journal of Zhejiang University SCIENCE B, 10, 57-66.
5. Zouboulis, C. C., & B?hm, M. (2004). Neuroendocrine regulation of sebocytes–a pathogenetic link between stress and acne. Experimental dermatology, 13, 31-35.
6. Sauder, D. N. (1990). The role of epidermal cytokines in inflammatory skin diseases. Journal of investigative Dermatology, 95(5).
7. Wittmann, M., McGonagle, D., & Werfel, T. (2014). Cytokines as therapeutic targets in skin inflammation. Cytokine & Growth Factor Reviews, 25(4), 443-451.
8. Evers, A. W. M., Verhoeven, E. W. M., Kraaimaat, F. W., De Jong, E. M. G. J., De Brouwer, S. J. M., Schalkwijk, J., ... & Van De Kerkhof, P. C. M. (2010). How stress gets under the skin: cortisol and stress reactivity in psoriasis. British Journal of Dermatology, 163(5), 986-991.
9. Jovi?, A., Marinovi?, B., Kostovi?, K., ?eovi?, R., Basta-Juzba?i?, A., & Bukvi? Mokos, Z. (2017). The impact of psychological stress on acne. Acta Dermatovenerologica Croatica, 25(2), 133-133.
10. Mufaddel A, Elnour AA, Omer AA, et al. Psychiatric comorbidity in patients with acne. Open J Psychiatry 2017; 07: 176–185.
11. Halvorsen JA, Stern RS, Dalgard F, Thoresen M, Bjertness E, Lien L. Suicidal ideation, mental health problems, and social impairment are increased in adolescents with acne: a population-based study. J Invest Dermatol. 2011;131(2):363-370. doi:10.1038/jid.2010.264
12. Jankowiak B, Kowalewska B, Krajewska-Ku?ak E, et al. Stigmatization and quality of life in patients with psoriasis. Dermatol Ther 2020; 10: 285–296.
13. Esposito M, Saraceno R, Giunta A, et al. An Italian study on psoriasis and depression. Dermatology 2006; 212: 123–127.