Comprehensive Mpox Detection Kits (RDTs and NAATs)

WHO Director-General Dr Tedros Adhanom Ghebreyesus has determined that the upsurge of mpox in the Democratic Republic of the Congo (DRC) and a growing number of countries in Africa constitutes a public health emergency of international concern (PHEIC) under the International Health Regulations (2005) (IHR). Unlike the last outbreak in 2022, which particularly affects?communities of men who have sex with men.?The mpox this year is spreading person to person, often via sexual contact, but also through other physical and face-to-face contact, or via contaminated bedding or towels. Moreover, children were reported vulnerable in this outbreak as 70% cases in DRC are under 18s and accounts for 85% of death of Mpox in the country.

Macro & Micro-Test has developed comprehensive NAATs?and rapid tests (Clade I & II covered)?for mpox detection so as to assist mpox diagnosis and its timely treatment and effective prevention measures.

Option 1: Monkeypox Virus Antigen Detection Kit?(Immunochromatography)

- Easy sampling (rash fluid/throat sample) and fast results within 15 min;

- High sensitivity with LoD of 20pg/mL?covering Clade I & II；

- High specificity with no cross-reactivity with smallpox virus, varicella zoster virus, rubella virus, herpes simplex virus, etc.

- Wide application such as customs, CDCs, pharmacies, clinics, hospitals or at home;

- OPA of 96.4% compared with NAATs and OPA of 96.7% compared with clinical diagnosis results.

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Option 2. Monkeypox-virus IgM/IgG Antibody Detection Kit?(Immunochromatography)

- Easy instrument-free operation and fast results within 10 min;

- High sensitivity and specificity?covering Clade I & II；

- Identifies IgM and IgG to decide mpox infection stages;

- Wide application such as customs, CDCs, pharmacies, clinics, hospitals or at home;

- Appropriate for large-scale screening of suspected mpox infection.

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Option 3. Monkeypox Virus Nucleic Acid Detection Kit (Enzymatic Probe Isothermal Amplification)-Lyophilized

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- High sensitivity with LoD of 200Copies/mL with IC,?equals to florescence PCR;

- High specificity without cross reactivity with smallpox virus, vaccinia virus, cowpox virus, mousepox virus, herpes simplex virus, varicella-zoster virus, and human genome, etc.;

- Easy sampling (rash fluid/throat sample) and fastest positive result within 5 min;

- Excellent clinical performance covering Clade I & II with PPA of 100%, NPA of 100%, OPA of 100% and Kappa Value of 1.000 compared with Fluorescence PCR kit;

- Flexible scenarios in clinics, healthcare center,?together with Easy Amp for?on-demand detection;

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Option 4: Monkeypox Virus Nucleic Acid Detection Kit (Fluorescence PCR)?-Lyophilized

- Dual?gene targeted with high sensitivity of LoD of 200 copies/mL?;?

- Flexible sampling of rash fluid, throat swab and serum;

- High specificity without cross reactivity with smallpox virus, vaccinia virus, cowpox virus, mousepox virus, herpes simplex virus, varicella-zoster virus, and human genome, etc.;

- Excellent clinical performance covering Clade I & II with PPA of 100%, NPA of 100%, OPA of 100% and Kappa Value of 1.000 compared with sequencing;

- Compatible with mainstream Fluorescence PCR Systems?and Eudemon? AIO800 Automatic Molecular Detection System;

- Flexible scenarios for hospitals, CDCs and labs;

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