China AI Hospital-Town launched, 7 People Cured of HIV, 1st Total Artificial Heart Implant, Bioprinted Tissue and Humanoid Robots at Work, CrowdStrike

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Pharma Round-up:

• 辉瑞 is advancing the fight against obesity with #danuglipron, a once-daily oral GLP-1 receptor agonist, now moving to dose optimization studies and large-scale clinical trials to ensure safety and efficacy. ????
• Grünenthal Group has acquired Valinor Pharma (acquired by Grünenthal) for $250M, expanding its U.S. market presence with #Movantik, and has invested over $2.2B in M&A since 2017. ????

Cancer Treatments

• Ron Haufler , a B.C. man with terminal colon cancer, is fighting to bring histotripsy, a non-invasive cancer treatment approved in the U.S., to Canada while fundraising over $100,000 for his own procedure. ??????
• New research from 加拿大麦吉尔大学 and Baylor College of Medicine brings hope for treating the rare and aggressive childhood brain tumor PFA ependymoma by targeting unique genomic structures known as TULIPs. ????
• Merck Canada 's "Practice Skintimacy" campaign aims to combat rising melanoma rates by promoting awareness, encouraging regular self-examinations, and emphasizing sun safety practices. ????
• The MHRA has approved #capivasertib, a new breast cancer drug, which, with #fulvestrant, greatly extends survival for advanced hormone receptor-positive, HER-2 negative cases. ????

Health Canada

• Health Canada | Santé Canada has approved #Tagrisso by 阿斯利康 , with chemotherapy for first-line treatment of EGFR-mutated advanced lung cancer, offering nearly nine months longer median progression-free survival than standard treatments. ????

• Ottawa is investing $48 million to enhance health workforce planning, improve physician data management, and support healthcare research and initiatives, including funding for Clinique Mauve to aid marginalized communities. ?????

• Following a 美国加州大学伯克利分校 study finding metals like lead and arsenic in tampons, Health Canada | Santé Canada is reviewing the findings before issuing any advisories or recommendations. ??????

FDA

• SUN PHARMA ’s #Leqselvi, an oral JAK inhibitor, has been FDA-approved for severe alopecia areata, joining 礼来 ’s #Olumiant and 辉瑞 ’s #Litfulo in treating this autoimmune condition. ?????

• A regulatory gap in FDA rules is flooding the US market with unregulated #Ozempic knockoffs, creating a billion-dollar market for unreliable weight-loss drugs amid shortages of approved medications. ?????

• The Ultrahuman Ring Air is now the first smart ring to receive FDA approval for detecting atrial fibrillation (AFib), enhancing its health tracking capabilities. ?????

BioTech & Research Round Up

• A $200 million federal-B.C. partnership with Aspect Biosystems will create over 200 jobs and advance bioprinted tissue therapeutics for serious diseases in B.C. ????

• 诺华 has struck a $150 million deal with Dren Bio, Inc. to develop new bispecific antibodies for cancer, with potential milestone payments reaching up to $2.85 billion. ?????

• Legend Biotech , known for its CAR-T therapy #Carvykti, has received a takeover bid and engaged Centerview Partners to explore options, leading to a notable increase in its stock price. ?????

• Scientists, including Holly Ingraham from University of California, San Francisco and Sundeep Khosla from Mayo Clinic , have discovered a new hormone, "maternal brain hormone," that significantly strengthens bones in lab studies, potentially leading to new treatments for fractures and osteoporosis. ?????

• Researchers from University Hospital Bonn, including Julius Ameln and Frank G. Holz , have identified early vision loss in age-related macular degeneration (AMD) using new imaging techniques, highlighting iRORA lesions that may improve early detection and treatment. ?????

• A new patient, known as "The Next Berlin Patient," has been declared cured of HIV after a bone marrow transplant from a donor with the CCR5 delta-32 gene mutation, offering hope for broader HIV cures through partial gene mutations. ?????

• Charles River Laboratories and Sanofi are partnering to develop virtual control groups using historical data and machine learning, aiming to reduce live animal use in preclinical research as part of a $300 million initiative for alternative testing methods. ????

Tech Trends

• 三星电子 has launched the Galaxy Watch7 and Galaxy Watch Ultra, featuring advanced health sensors and Galaxy AI integration for personalized wellness insights and comprehensive health monitoring. ????

• The #BiVACOR Total Artificial Heart, using magnetic levitation for smoother blood flow and reduced wear, has been successfully implanted at CHI St. Luke's Health - Baylor St. Luke's Medical Center as part of an FDA feasibility study. ????

• Researchers from 美国加州大学圣迭戈分校 have created a wearable device that measures cervical nerve activity, offering early diagnostic markers for PTSD and sepsis by detecting changes in autonomic nervous system responses. ?????

• Dr. Wang Wei and 术理创新 Innovation are transforming stroke recovery with brain-computer interface technology, enabling motor function restoration and improved quality of life using brainwave signals. ?????

• Lee M. Mandel, MD, FACS in South Florida is using 4-D imaging technology to enhance precision and outcomes in sinus surgeries, leading to better breathing and faster recovery for patients. ?????

From the World of AI

AI APPLICATION IN HEALTHCARE

• 清华大学 has launched China’s first AI hospital town, "Agent Hospital," where virtual doctors and patients use advanced language models to simulate medical treatments and diagnoses, transforming healthcare training and service delivery. ?????

• Insilico Medicine has launched #DORA, an AI assistant for drafting medical research papers, alongside secure offline analysis engines and an open-source AI program for aging research, using multiple LLMs to boost accuracy and support researchers. ????
• London-based 迈达普 has secured $80M to launch an AI-powered cloud platform, enabling startups and pharmaceutical companies to quickly prototype, launch, and scale regulated digital health apps using generative AI technology. ????

• Researchers at 英国伦敦大学 - 伦敦国王学院 and University College London Hospitals NHS Foundation Trust have used Cambridge-1 supercomputer to develop an AI model that generates high-resolution, synthetic 3D brain images, aiding in the study and treatment of brain diseases. ?????

• Arianna Huffington and OpenAI CEO Sam Altman have launched Thrive AI Health, an AI-powered health coach offering personalized advice on sleep, nutrition, fitness, and stress management, supported by the OpenAI Startup Fund. ?????

• Healthcare leaders are keen to adopt generative AI to improve operations, with many already pursuing or implementing AI despite concerns about risks and technical challenges, highlighting the need for strategic partnerships and strong governance. ????

• Writer has launched two specialized AI models, #Palmyra-Med-70b for healthcare and #Palmyra-Fin-70b for financial services, providing high accuracy and tailored capabilities across multiple platforms. ????

• GE医疗 is acquiring Intelligent Ultrasound Group PLC 's AI technology for $51 million to enhance its ultrasound portfolio, complementing its previous acquisition of Caption Health’s AI-powered coaching software. ????

• Ferrum Health, Inc. and PaxeraHealth have partnered to integrate Ferrum Health, Inc. 's AI platform with PaxeraHealth 's imaging solutions, aiming to enhance patient care through seamless AI deployment in clinical workflows. ????

STRATEGY FOR AI

• Canada is investing $15 million in the Health Compass II project to develop AI technologies that boost patient engagement and streamline administrative tasks, contributing to a total budget of $44 million. ??????

• B.C. is investing $2.65 million in AI and digital tools to speed up disease diagnoses, including cancer, by enabling secure sharing of high-quality images for faster assessments and second opinions. ?????

• Key competition authorities from the EU, UK, and US have committed to collaborating on AI policy to ensure fair markets, prevent power concentration, and promote interoperability and choice in the AI ecosystem. ?????

• OpenAI supports three Senate bills, including the Future of AI Innovation Act, which aims to establish a U.S. AI Safety Institute and bolster AI education and research, to influence AI regulation and promote safe development. ??????

BOTS & IDENTITY

• The Istituto Italiano di Tecnologia ’s SoftFoot Pro is a flexible, motorless, and waterproof prosthetic foot designed to mimic human anatomy, offering improved stability and adaptability on uneven and slippery terrains, tested with both humans and robots. ?????

• Ben-Gurion University of the Negev ’s Physical AI Lab has developed 3D-printable composite materials with mixed-ionic-electronic conductivity, mimicking natural sensory organs to create advanced multifunctional sensors for robotics and healthcare. ??????

• Microbot Medical has completed the first clinical trial of its Liberty endovascular robotic surgical system, marking a key milestone in its efforts to advance robotic-assisted procedures and support future FDA submissions. ?????

• Boston-based Perceptive Technologies has completed the world’s first fully automated dental procedure using its AI-driven robotic system, enhancing the speed and precision of crown placements. ?????

?BIG TECH NEWS IN AI

GOOGLE

• 谷歌 will use AI to enhance the U.S. broadcast of the Paris Olympics, providing AI-generated insights and recaps for a richer viewing experience. ?????

• 谷歌 has unveiled #NeuralGCM, a hybrid AI-physics weather model designed to improve predictions of large-scale climate events. ?????

• Google Premium AI ’s AlphaProof and AlphaGeometry 2 have achieved significant results in the Math Olympiad, advancing mathematical reasoning and problem-solving capabilities. ????

META

• Meta has launched #Llama 3.1, its largest open-source AI model, claiming it outperforms rivals and may soon surpass ChatGPT in usage. ?????

• Meta is ending its celebrity chatbot project to focus on AI Studio, a new platform that enables creators to build personalized AI bots. ?????

• Meta 's new 'Imagine Me' feature allows US users to generate and customize AI images of themselves based on creative prompts. ?????

AMAZON

• 亚马逊 's #Rufus AI shopping assistant is now available to all US users, offering answers to product-related questions and updates on orders. ?????

• GE医疗 and Amazon Web Services (AWS) are partnering to develop generative AI tools aimed at enhancing medical data analysis. ?????

• 亚马逊 has upgraded its AI offerings to boost performance and compete with rivals like OpenAI and 谷歌 . ????

MICROSOFT

• A faulty CrowdStrike update led to a global tech outage, disrupting U.S. hospitals with critical "blue screen" errors for 微软 users and delaying emergency operations. ?????

• 微软 is collaborating with Mass General Brigham and the 美国威斯康星大学麦迪逊分校 to advance AI in medical imaging. ?????

• 微软 ’s VALL-E 2 achieves human-level voice replication but is restricted to research use due to concerns about potential misuse. ??????

NVIDIA

• 英伟达 aims to transform healthcare with AI technology that enhances patient interactions and medical imaging, partnering with companies like Hippocratic AI. ?????

• 英伟达 has announced new AI software advancements that enhance virtual world simulations for industrial applications and improve humanoid robot training. ????

• 英伟达 ’s #fVDB framework enables high-resolution, large-scale virtual environments for AI applications in autonomous vehicles and smart cities. ?????

Topics:

#AI #Amazon #TechCompetition #Innovation #TechOutage #CrowdStrike #HealthcareIT #VoiceAI #Microsoft #VALL-E2 #EthicalAI #EmergencyResponse #MedicalImaging #Nvidia #PatientCare #VirtualEnvironments #SmartCities #ObesityTreatment #PharmaInnovation #Pfizer #PharmaAcquisition #AIStudio #Meta #Chatbots #CreatorTools #Grünenthal #ValinorPharma #HealthInnovation #CancerTreatment #Histotripsy #HealthcareAdvocacy #HopeForHealth #ChildhoodCancer #BrainTumorResearch #McGillUniversity #MedicalBreakthrough #SkinCancerAwareness #MelanomaPrevention #SunSafety #MerckCanada #BreastCancer #MHRA #NewDrug #LungCancer #Tagrisso #HealthCanada #HealthcareInvestment #Ottawa #HealthWorkforce #CommunitySupport #TamponSafety #MetalsInProducts #AIModels #HealthcareAI #FinTech #WriterInc #IndustrialSimulation #RobotTraining #PublicHealth #AlopeciaAreata #FDAApproval #SunPharma #HairLossTreatment #Ozempic #HealthTech #WearableTech #GalaxyWatch #SamsungInnovation #Olympics2024 #BroadcastInnovation #Google #AmazonAI #ShoppingAssistant #CustomerService #MedicalData #GEHealthCare #AWS #ArtificialHeart #MaglevTechnology #FDAStudy #FDARegulations #WeightLoss #DrugSafety #AFibDetection #SmartRing #Bioprinting #JobCreation #FederalPartnership #CancerResearch #Novartis #DrenBio #BiopharmaDeal #LegendBiotech #CAR-T #StockMarket #BiotechNews #BoneHealth #Osteoporosis #HormoneResearch #AMD #VisionLoss #ImagingTech #HIVCure #GeneTherapy #CCR5Mutation #AlternativeTesting #PreclinicalResearch #AnimalWelfare #PTSD #Sepsis #NerveActivity #StrokeRecovery #BrainTech #InnovationInScience #SinusSurgery #4DImaging #SouthFlorida #AIinMedicine #ResearchTools #InsilicoMedicine #AgingResearch #DigitalHealth #Huma #TechInvestment #King'sCollegeLondon #PersonalizedCoaching #ThriveAI #OpenAI #GenerativeAI #AIAdoption #MedicalTechnology #Ultrasound #FerrumHealth #PaxeraHealth #HealthCompassII #OpenSource #Llama31 #CanadaInvests #DiseaseDiagnosis #BCInvestment #AIRegulation #SenateBills #AIEducation #Prosthetics #InnovativeDesign #SoftFootPro #3DPrinting #Robotics #MicrobotMedical #DentalAI #Perceptive #WeatherForecasting #ClimateScience #MathOlympiad #AIImages #Personalization

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