Cervical cancer screening report

Two important inspection items for cervical cancer screening - TCT (liquid-based thin-layer cell test) and HPV (human papillomavirus test). What do these inspection reports look like?

1. What is TCT?

There are some shed cells in the cervix of women. TCT examination uses liquid-based thin-layer cell detection technology to classify and diagnose these cells to determine whether the cells are cancerous. Doctors can also use this technology to find out whether there are precancerous lesions, microbial (such as mold, trichomoniasis, virus, chlamydia, etc.) infection and other phenomena.

The standard report sheet includes the following key sections: sample satisfaction, epithelial cell analysis (squamous epithelial cell & glandular epithelial cell analysis), microscopic cell map, physician's diagnosis results and opinions. Of course, many hospitals will also produce this kind of report, simplifying the difficulty of understanding, but in fact, the general meaning is similar.

1. No intraepithelial lesions or malignant cells (NILM)

●means: cervical cells are normal, no special treatment is required.

2. Inflammation (including mild inflammation, moderate inflammation, severe inflammation)

●Meaning: There may be cervical inflammation, and malignant lesions can be basically ruled out

●Treatment: It is recommended to go to the hospital for further examination, and the doctor will formulate a treatment plan according to the type of inflammation.

3. Mold infection, Trichomonas infection, Actinomycete infection (or bacterial overgrowth)

●means: the normal flora of the vagina is out of balance, or there is the invasion of pathogenic microorganisms such as Trichomonas, which leads to infection.

●Treatment: The doctor may recommend another routine leucorrhea and bacterial vaginosis examination, and then formulate a treatment plan based on the examination results.

4. ASC-US, squamous cells of atypical significance or atypical squamous cells of indeterminate significance

● Meaning: This result suggests that it is uncertain whether these cells are abnormal.

●Treatment: It is recommended to check "high-risk HPV".

① HPV is negative, and there are no symptoms (such as irregular vaginal bleeding, intercourse bleeding, bloody leucorrhea, etc.), TCT can be reviewed after 1 year of observation;

② HPV is negative, but there are symptoms, suggesting that there may be inflammation, and TCT can be re-examined after 3-6 months of anti-inflammatory treatment;

③ If HPV is positive, colposcopy + cervical biopsy is recommended.

5. ASC-H, atypical squamous cells do not exclude high-grade squamous intraepithelial lesions

●Meaning: Although the meaning cannot be clearly defined, it tends to have lesions.

●Treatment: It is recommended to check "high-risk HPV" and perform colposcopy + cervical biopsy.

6. LSIL, low-grade squamous intraepithelial lesion

Meaning: There may be cervical precancerous lesions, but don't be too nervous, this stage

Most of the precancerous lesions resolve spontaneously.

●Treatment: It is recommended to check "high-risk HPV" and perform colposcopy + cervical biopsy.

7. HSIL, high-grade squamous intraepithelial lesion

●Meaning: There are suspicious precancerous cells, and further diagnosis and treatment are needed, otherwise, the possibility of developing into cancer is high.

●Treatment: It is recommended to check "high-risk HPV", perform colposcopy + cervical biopsy as soon as possible, and perform lesion resection (leep circumcision or cold-knife conization) according to the degree of lesions.

8. AGC, atypical glandular cells

●means: very likely to be precancerous lesions.

●Treatment: perform colposcopy + cervical biopsy + cervical canal scratching and curettage as soon as possible to confirm the diagnosis.

2, what is HPV?

HPV, short for human papillomavirus, is a small DNA virus of many types that can cause a variety of benign papillomas or warts of human skin and mucous membranes. Certain types of HPV infection are also Potential carcinogenicity. The HPV test mainly detects whether a person carries the HPV virus. It can be checked for HPV infection by dye microscopy, HPV DNA detection, or serological tests. Genital HPV infection in women is a common sexually transmitted disease. Sexually active women may be 50% infected with at least one type of HPV. Since human papillomavirus infection is the cause of cervical cancer, we must pay attention to this infection and pay attention to the examination of HPV.

The majority of reports are HPV typing tests, ranging from:

14 high-risk HPV types, including HPV16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66, 68)

7 low-risk HPV types, including HPV6, 11, 42, 43, 44, 53, cp8304

● Two or more HPV subtypes are positive for HPV multiple infection.

● Everyone should communicate with the doctor according to their own situation during the re-examination, and can only test for "high-risk HPV".

The Bioperfectus Technologies Human Papillomavirus (HPV) Genotyping Real Time PCR Kit is an in-vitro diagnostic (IVD) kit used for the detection of 21 different Human Papillomavirus (HPV) in patient specimens. The test specifically identifies 18 high-risk HPV types (16, 18, 31, 33, 35, 39, 45,51, 52, 53, 56, 58, 59, 66, 68, 26, 73, and 82) and three low-risk HPV types (6, 11, and 81).

The Bioperfectus Technologies Human Papillomavirus Real Time PCR Kit is intended for the in-vitro qualitative detection of nucleic acids of 18 HPV types (16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66, 68, 73, 53, 82, and 26) in cervical exfoliated cells, and genotyping for HPV16 and HPV18, but not for the other HPV types.