Bruker BioSpin Newsletter #11

Celebrating 80 Years of EPR

As we celebrate the 80th anniversary of EPR in 2024, we are proud to continue our tradition of excellence and innovation in #EPR technology, and we remain committed to supporting the EPR community. Meet us at conferences and events this year to celebrate with us and to learn more about our unique mix of reliable and versatile solutions.

Read more: https://goto.bruker.com/3VQi7Me

What's the Buzz? It's Avance Chemical Profiling!

Data processing, interpretation, and automatic report generation are crucial steps in recurring tasks such as formulation screening within the chemical manufacturing industry. Bruker’s new NMR-based Avance Chemical Profiling Module simplifies these tasks. It enables the identification and quantification of constituents in a mixture of raw materials, process intermediates, and final product formulations, enhancing both quality and efficiency across R&D, pilot, and large-scale production processes.

Learn more: https://goto.bruker.com/49lfzZQ

Multimodal Assessment of Hypoxia in Tumors: From the Lab to the Clinic

Thursday, 25 April 2024, 16:00 CET

#Hypoxia occurs due to inadequate oxygen supply and greatly influences solid tumor development and resistance to treatment. PET/MRI can play a critical role in the diagnosis, treatment orientation, and subsequent management of brain tumors as it can provide complementary information regarding #tumor metabolic properties, particularly when performed simultaneously with advanced MRI techniques.

Register now: https://goto.bruker.com/43LnC0S

Enhancing Pharmaceutical Research - Customer Insight

Dr Jagadeesh Bharatam and his team at the CSIR-INDIAN INSTITUTE OF CHEMICAL TECHNOLOGY use #NMR to study the structural properties, impurities, and polymorphs of drug formulations in solid and solution states, with applications in drug evaluation, characterization, and design. They are also collaborating with Bruker to advance the field of solid-state NMR with novel techniques such as Hadamard NMR spectroscopy.

Download the article: https://goto.bruker.com/3U1sGe5

5th Annual Bruker MRI Award Finalists Have Been Chosen!

We were so thrilled to receive so many submissions this year. We had submissions from over 10 countries spanning three different continents. It was a tough decision but we have narrowed it down to a top three.

Congratulations to all the finalists!

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Cast your vote*: https://goto.bruker.com/3TFm1VP

*Voting is accepted until April 19, 2024

Precision Medicine Through Metabolomics Studies*

Prof. José M. Mato, Founder and Director of the CIC bioGUNE Center for Cooperative Research in Biosciences, Prof. Jesus Jimenez-Barbero , Scientific Director, and Dr. Oscar Millet , Principal Investigator, describe how the work of the center is helping to shape the future of healthcare, from diagnostics to precision medicine. Hear how high-throughput NMR methodology is essential in large-scale metabolomic studies to advance understanding of diseases such as liver disease, cancer and metabolic syndrome.

Watch the interview: https://goto.bruker.com/3xo3yWk

*Research use only. Bruker NMR instruments are not intended for use in clinical diagnostic procedures.

Probing Molecular Packing of Lipid Nanoparticles (LNPs) from 31P Solution and Solid-State NMR

Interested in adding an atomic resolution approach to your analytical workflow for LNP characterization? Within this study, scientists from 默克 & Co introduce 31P NMR methods to acquire structural and dynamic information about the phospholipid envelope of LNPs. Specifically, it demonstrates that the 31P chemical shift anisotropy (CSA) parameters serve as a sensitive indicator of the molecular assembly of distearoylphosphatidylcholine (DSPC) lipids within the particles. An analytical protocol for measuring 31P CSA is developed, which can be implemented using either solution NMR or solid-state NMR, offering wide accessibility and adaptability.

Read the article: https://goto.bruker.com/3PpSeyQ

Oligonucleotide-based Therapeutics: NMR Techniques for Characterization

On-Demand

In the free on-demand webinar*, "Oligonucleotide-based Therapeutics: NMR Techniques for Characterization", Celestine Chi ( 阿斯利康 ), Robert Brinson ( IBBR Institute for Bioscience and Biotechnology Research , National Institute of Standards and Technology (NIST) ), and Martial Piotto (#Bruker) discuss the latest advancements in NMR oligonucleotide-based drug characterization.

Watch the recording here: https://goto.bruker.com/3vCkNm4

*This webinar is a collaboration between PANIC NMR and Bruker.

Markus Jungen, SGF International e.V.

Many thanks to Markus Jungen , Technical Manager at SGF International e. V. , for his testimonial!

"The Juice-Profiling methodology, a robust tool, not only expedites the evaluation of authenticity in fruit juices but also extends its reach to encompass vegetable juices. By harmonizing quantitative scrutiny of constituent elements and intricate statistical analyses of profiles, including provenance, this method offers a comprehensive and efficient means of discerning the authenticity of both fruit and vegetable juices."

Learn more about Juice-Profiling: https://goto.bruker.com/4aF8cNI