Boost your analysis by coupling IEX and HIC to MS
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Today you will learn how to couple chromatographic modes using high salt concentrations to mass spectrometry, to simplify your lab workflow.??
Boost your analysis by coupling IEX and HIC to MS
Navigate your biomolecule analysis with confidence by leveraging YMC's proven expertise. By combining ion exchange (IEX) and hydrophobic interaction chromatography (HIC) with our precisely developed columns, you can analyse monoclonal antibodies (mAbs), antibody-drug conjugates (ADCs), and proteins in biologically relevant conditions detecting with mass spectrometry (MS).
This approach helps you achieve dependable results by minimising isolation artefacts and ensuring consistent reproducibility. Empower your research with solutions designed to deliver both accuracy and reliability.
The implementation of MS detection already succeeded for the CEX analysis of the NISTmAb and MS could also be combined with AEX for the determination of IgG4-based mAbs.
A similar setup can be used for the characterisation of mAbs and related products via HIC-MS.