Biweekly Research News Digest
This newsletter is designed to share with you research news in various fields where applications of gene sequencing can be found. It will share research findings from Novogene’s customers. By sharing insights from the most prestigious research teams, it is intended to call your attention to the latest applications of sequencing in life sciences and biomedical research and inspire your research.
Welcome back to the Biweekly Research News Digest. Firstly, we extend our heartfelt gratitude to all who participated in last week's poll, where we sought your input on the content you wish to see in our newsletter. In the poll reseaults, application of sequencing?in the field of agricultural research?emerged at the top of the ranking. In response, as we promised in the poll, this issue of Biweekly Research News Digest?will feature?five articles?presenting agricultural research that used various sequencing technologies. These investigations explore avenues for enhancing hybrid breeding techniques for rice, unraveling the mystery behind the declining yields of wheat in lands subjected to continuous cropping, and devising strategies to bolster the health of broiler chickens. They?endeavor not only to deepen our comprehension of crop and poultry growth but also to offer novel pathways for advancing crop cultivation and animal husbandry.
Understanding Postzygotic Reproductive Isolation: Insights from the Function of HWS1 and HWS2 in Asian and African Rice
Postzygotic reproductive isolation typically causes irreversible species divergence, often resulting in hybrid sterility, necrosis/weakness, or lethality in offspring generations. In?a recent article published in?Nature Communications, researchers from the Chinese Academy of Sciences clarified the role?of HWS1 and HWS2 in causing complete interspecific incompatibility between Asian and African rice. They demonstrated that these genes control vital pathways related to pollen and seed development by affecting vitamin metabolism and lipid synthesis. Additionally, they did evolutionary analysis of HWS1/2 and suggested?that the gene pair experienced incomplete lineage sorting and multiple gene duplication events?in the process of?speciation. These discoveries not only enhance our comprehension of speciation mechanisms but also offer insights for improving hybrid breeding techniques.
Unraveling Yield Decline Associated with?Successive Winter Wheat Rotations: Insights from Outdoor Experiment and Soil Analysis
Although it has been widely recognized that successive winter wheat (WW) rotations are closely related to?significant decline in yield,?the mechanism underlying the association is underexplored. A joint research team from German institutions conducted outdoor experiment?with sandy loam soil to analyze WW growth in various rotational positions, aiming to?specify the mechanism. They?employed zymography and glucose (GLU) imaging, observed changes in enzyme activity and glucose release patterns in the rhizosphere, and?measured biochemical and microbial properties?of the bulk soil and the rhizosphere. They found?that successive WW rotations led to reduced plant biomass. In addition, they discovered?differences in root characteristics, soil nutrient concentrations, and microbial community dynamics among rotational positions. This study elucidated the interaction between soil properties, plant growth, and microbial communities, providing insights into the mechanisms driving yield decline in successive?WW rotations.
Deciphering the Role?of Gibberellic Acid in Enhancing Cotton Fiber Yield and Quality
The modification of gibberellin (GA) signaling?increased crop yield, but our understanding of GA signaling cascade in cotton is still limited, hampering efforts to develop new cotton varieties and improve yield and quality. Scientists from Shaanxi Normal University?located?in China elucidated how GA promotes cotton fiber elongation. They discovered that GA triggers the degradation of DELLA protein GhSLR1, releasing transcription factors GhZFP8 and GhBLH1. These factors activate genes involved in very long-chain fatty acids (VLCFAs) biosynthesis and plant cell elongation, ultimately fostering cotton fiber elongation. This newfound understanding provides a pathway to enhance both the quality and the yield of cotton fibers.
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Alleviating Heat Stress Effects on?Broilers: Protective Role of Lactobacillus rhamnosus
Heat stress (HS) represents a significant challenge for broilers due to their high metabolic rate and lack of sweat glands. In a recent article published in the Science of the Total Environment, researchers investigated the impact of a cyclic chronic HS on?finisher?broilers and examined the protective effects of Lactobacillus rhamnosus (L. rhamnosus). They observed that chronic HS led to reduced?diversity of cecal microbiota?and?compromised integrity of?the intestinal barrier, resulting in gut leak and?reduction in body weight. Oral supplementation of L. rhamnosus?improved cecal microbiota composition?and?raised?the transcription of tight junction proteins, leading to?suppressed?expression of?pro-inflammatory cytokines?and improved digestive capability. The intervention facilitated?intestinal development?and?epithelial maturation. This?study?offers insights into potential strategies for improving poultry health under stressful conditions.
Exploring Genetic Diversity and Population Dynamics of Ethiopian Goats: Insights from Genome Analysis
In an article recently published in Scientific Data, a?collaborative team of researchers from Ethiopia, China, the United Kingdom, and the United States analyzed 57 Ethiopian goat genomes from 12 populations. Their study?yielded approximately 2 terabytes of raw data, achieving a mapping success rate of 99.8%. It?also identified?24.76 million SNPs. These findings offer?significant potential for the study of?the population structure?and genome dynamics?of goats.
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About Novogene
Novogene is a leading company that applies advanced molecular biotechnology and high-performance computing in the research fields of life science and human health. Since its establishment in March 2011, Novogene has been dedicated to becoming a global leader in offering genetic science services and technology products. The company has successfully established cutting-edge platforms for high-throughput, large-scale gene sequencing, and high-performance computing. With a strong global presence, Novogene has provided its services to more than 7,000 customers worldwide, spanning 90 countries and regions across six continents. As of June 2023, Novogene has made significant contributions to the scientific community, co-publishing and/or being acknowledged in over 20,000 articles in the Science Citation Index. These publications have collectively garnered an impressive accumulative impact factor of 120,000+.
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