Bi-Monthly Newsletter Tobacco & Nicotine

Top Industry Headlines

• U.S. FDA Authorizes Marketing of Four Menthol-Flavored E-Cigarette Products After Extensive Scientific Review
• Study Finds Smokers Confused About Relative Risk
• e-Cigarette market expected to grow 12.8% by 2028
• Flavor Bans Threaten Smoke-Free Ambitions
• U.S. FDA Rescinds MDOs Issued to JUUL Labs in June 2022; Applications Returned to "Pending" Status
• Justice Department and FDA Announce Federal Multi-Agency Task Force to Curb the Distribution and Sale of Illegal E-Cigarettes

Labstat's Greensboro, N.C., Lab Earns ISO 17025 Accreditation

We're happy to inform our clients that we've successfully completed the A2LA evaluation process and have earned ISO 17025 accreditation for?chemistry methods for tobacco and tobacco products.

View the full scope of accreditation on our website.??

Join our expert panel this week to hear the latest on cannabis device performance and safety.?

This webinar will cover...

• Device performance and the user experience.
• Regulatory requirements and compliance for upcoming regulatory standards.
• OCS stipulations and market viability.
• Engage with industry experts in a Q&A session to address specific questions and concerns.

Can't make it? Register and we'll email you the recording.?

Register for the Webinar

GC/HRMS Analysis of E-Liquids Complements In Vivo Modeling Methods and Can Help Predict Toxicity

Recent research published in ACS Omega reveals significant findings on the toxicity of e-liquids used in vaping. The study used GC/HRMS analysis to compare chemical signatures in vaped and unvaped e-liquids, identifying potential respiratory irritants.

In vivo experiments with zebrafish and mice models demonstrated that certain flavored e-liquids, particularly menthol, can induce oxidative stress and inflammatory responses.

These insights are crucial for understanding the health implications of e-cigarette use and highlight the need for stringent regulation and assessment of e-liquid components for public safety.

Read the Article

Applying New Approach Methodologies to Assess Next-Generation Tobacco and Nicotine Products

In vitro toxicology is advancing rapidly through the integration of computational approaches and human tissue systems, leading to significant improvements in safety evaluations of new consumer products.

New approach methodologies (NAMs) are being adopted across various industries for chemical testing and drug screening, driven by the need for reliable, human-relevant methods.

This review highlights the application of NAMs in assessing next-generation tobacco and nicotine products (NGPs), emphasizing the importance of using appropriate in vitro models, hazard identification screening, and test article characterization.?

Read the Article

Swedish Dentists?Endorse?Nicotine Pouches With Built-In Gum Protective Layer?

In a trial supervised by dentist Mathias Ahl, 23 Swedish dentists switched to Sting Free pouches for 5 weeks, resulting in a dramatic improvement in oral health.

The incidence of irritated gums dropped from 43.5% to 4.3%, and the presence of oral mucosal snus lesions decreased from 95.7% to 65.2%.?

Consequently, 20 out of the 23 dentists endorsed Sting Free pouches for patients who are unable or unwilling to quit using these products.?

Read the Article

Upcoming Conferences and Events

The Tobacco Products Scientific Advisory Committee; Notice of Meeting

Silver Spring, MD, USA - June 26?

77th Tobacco Science Research Conference (TSRC)

Atlanta, GA, USA - Sept. 8-11

Global Tobacco and Nicotine Forum (GTNF)?

Athens, Greece - Sept. 24-26

CORESTA?

Edinburgh, UK - Oct. 13-17