Astragalus Polysaccharides（Hastra）: Boosting Immunity Through Liver Protection, Anti-Inflammation, and Gut Microbiota Enhancement

Astragalus, also known as Huangqi, is a widely used herb in traditional Chinese medicine. Astragalus polysaccharides (APS), natural active substances derived from this plant, have gained significant traction in the poultry farming industry in recent years. Renowned for their natural origin and proven efficacy, APS has become an increasingly popular choice among farmers aiming to improve livestock health and productivity.

Research and Applications in Poultry Farming

The Vegamax team has been committed to exploring APS applications in livestock and poultry farming. Our extensive research and experimental studies have laid a robust scientific foundation for its use in poultry production, yielding promising results.

How Does Astragalus Support Broiler Growth and Health?

1. Antioxidant Properties: Protecting the Liver

In intensive poultry farming, broilers are prone to oxidative stress, which can impair growth and lower immunity. The liver, a vital organ responsible for detoxification and combating pathogens, is highly susceptible to damage from toxins, free radicals, medications, and viruses.

Studies have shown that lipopolysaccharides (LPS) can cause acute liver damage in broilers, disrupting hepatic structure and function. Supplementing diets with APS significantly boosts antioxidant enzyme activity (T-SOD, T-AOC, and GSH), while reducing markers of oxidative stress like MDA and ROS. These effects help mitigate oxidative damage caused by LPS, restoring liver health.

Furthermore, APS supplementation enhances mitochondrial energy metabolism and biosynthesis by upregulating liver protein expression of SIRT1, NRF1, and PGC-1α. This restores mitochondrial function and reduces oxidative stress.

2. Supporting Gut Health

The gut microbiome plays a pivotal role in poultry health. Adding APS to broiler feed has been shown to positively influence gut microbiota composition.

• Improved Microbiota Balance: APS increases the relative abundance of beneficial Bacteroidota while reducing Firmicutes, adjusting the F/B ratio to maintain a healthier gut environment.
• Enhanced Beneficial Bacteria: Levels of Alistipes and Prevotellaceae_NK3B31_group — beneficial bacteria — are notably elevated in broilers fed APS, improving gut microbial diversity and overall gut health.

3. Boosting Immunity and Disease Resistance

Strong immunity is crucial for broiler health and performance. Supplementing broiler diets with APS has demonstrated:

• A significant increase in the Bursa of Fabricius index and serum immunoglobulin levels, key indicators of immune function.
• Enhanced development of immune organs such as the thymus, spleen, and bursa, contributing to improved disease resistance.

Future Prospects for APS in Poultry Farming

Astragalus polysaccharides present vast potential for improving poultry health and productivity. At Vegamax, we are committed to advancing the scientific understanding and practical applications of APS in livestock farming. By providing scientifically-backed, effective solutions, we aim to empower farmers to achieve healthier livestock and greater operational success.

For more insights and solutions, visit our homepage: www.vegapharma.com.