Assess Biopharmaceutical Stability and Material Compatibility with QSense Sensors

In the biopharmaceutical industry, ensuring the stability and compatibility of drug formulations with various materials is crucial. At Biolin Scientific, we offer the QSense? sensor package, designed to mimic the surface properties of materials commonly used in biopharma, such as plastic packaging, glass containers, pre-filled syringes, and IV bags. These sensors enable detailed analysis of drug-surface interactions, facilitating early assessment of material compatibility and stability during drug formulation.

QSense QCM-D: A Powerful Technology for Biopharma

QSense QCM-D method allows for the evaluation of surface adsorption and desorption processes and changes in the structure of adsorbed layers throughout the lifecycle of pharmaceutical drugs. QSense can answer the following questions:

• How much antibody adsorbs to different surface materials?
• How are the molecules arranged at the surface?
• What surfaces may cause incompatibility issues?
• How does an excipient impact antibody adsorption?
• How do changes in concentration, pH, temperature, surface material, or surfactant type affect the adsorbed amount?

Suggested Sensors for Biopharma Industry

We offer a range of sensors tailored for different applications:

• Stainless Steel (SS2343): Surgical instruments, medical implants, sterilization trays
• Borosilicate Glass: Container glasses
• Polystyrene: Petri dishes, disposable labware
• Amorphous Fluoropolymer: Medical tubing, liners, bio-coating