Animal and Cellular Models in Metabolomics Research Volume 2

A special issue of?Metabolites?(ISSN 2218-1989). This special issue belongs to the section "Animal Metabolism".

Deadline for manuscript submissions:?15 November 2022.

Special Issue Information

Dear Colleagues,

Metabolomics, an essential tool of modern biochemical research, is no longer solely a hypothesis-generating platform, but rather is extensively used in hypothesis testing studies. Progress in gene manipulation techniques allows the turning on and off of particular enzymatic functions in a cell- or tissue-specific manner. High-throughput cell culture and animal model studies are increasingly popular. While many metabolic questions can be answered under well-controlled cell culture conditions, the true test is the transition from the dish to in vivo models.

We therefore invite research and review articles devoted to the various cell and animal models used in metabolic studies. The focus of this Special Issue involves technical approaches and the translation from cell to animal metabolic models. The topics include but are not limited to the use of cell culture and animal models in the exploration of single cell metabolism, high-throughput metabolomics, and the use of stable isotope tracers for metabolic flux analysis. Studies using genetic manipulations or in vivo dietary and pharmacological interventions are particularly welcome. Studies applying in vitro/in vivo imaging of metabolites with the use of DNP-NMR and MRI are highly anticipated. Finally, protocols describing experimental guidelines are also encouraged.

This Special Issue is open for submissions now. A proper extension may be granted, please kindly let us know in advance. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the Special Issue website.

Dr. Michal Ciborowski

Dr. Joanna Godzien

Dr. Stanislaw Deja

Guest Editors

Keywords

• Cell culture models
• Animal models
• Animal microbiome
• Tumour xenografts
• Targeted and untargeted metabolomics
• Metabolic flux analysis (MFA)
• Metabolic imaging DNP-NMR

More info: https://www.mdpi.com/journal/metabolites/special_issues/animal_metabolomics_Vol2