AMR Future Brief| How Are Innovations in Virology Shaping the Future of Public Health?

Virology is a rapidly expanding field in biotechnology and healthcare. Due to the increasing need for vaccines and antiviral drugs to combat diverse viral threats, which include seasonal flu and novel pandemics, the demand for their development has increased. This industry is essential for protecting public health and advancing scientific technology. Moreover, innovations in technology, particularly in molecular diagnostics and vaccine improvement, are leading this expansion.??

Recent advances, such as mRNA vaccines, have modified the approach to fighting viral infections, showing the potential to respond quickly to emerging threats. On the other hand, investors and researchers are eager to discover new possibilities in this field.? There is a high demand for antiviral treatment plans and advanced diagnostic tools, fueled by competitive dynamics in the pharmaceutical sectors. Therefore, these sectors hold the potential for considerable scientific discoveries at the same time playing an important role in safeguarding global health.?

Nanopore technology revolutionizes rapid virus detection?

Nanopore-based resistive-pulse sensing is an innovative technology in virology that helps in the detection and analysis of viruses. This technique uses extremely small pores known as nanopores to detect virus particles. When a virus passes through the nanopore, it alters the electrical current. By observing these changes, researchers can figure out the virus's size and quantity. One major advantage of RPS is that it does not require complicated labels or dyes. It offers direct and quick information about viruses, in contrast to traditional techniques such as PCR tests, which take more time and involve additional procedures.?

Nanopore sensors are gaining more importance, particularly for the rapid identification of various viruses. During the COVID-19 pandemic, researchers explored the potential of this technology for detecting SARS-CoV-2, the virus responsible for COVID-19. A recent survey published in Nature Nanotechnology (2023) indicates that nanopore-based sensors are useful in detecting viral infections at an early stage, thereby enhancing response efforts during outbreaks.?

These sensors are capable of identifying various virus-related particles, such as exosomes and virions, which are tiny particles generated by viruses. The ability to detect these particles in real-time aids in monitoring how viruses spread or evolve. This advanced technology has the potential to considerably enhance the diagnosis, monitoring, and response capabilities for viral diseases.?

RINK boosts startup ecosystem with new partnership with virology institute?

In February 2024, the Research Innovation Network Kerala, part of the Kerala Startup Mission, enhanced its collaboration with startups by having a productive visit to the Institute of Advanced Virology, an autonomous institute under Kerala's Department of Science and Technology. The event, held at the IAV Life Sciences Park, facilitated incubation opportunities for startups to collaborate with leading scientists in developing new products and services. Furthermore, attendees visited the central instrumentation facilities and participated in interactive sessions with experts, gaining valuable insights into various advances in virology and life sciences.?

This initiative reinforced RINK's commitment to promoting knowledge-sharing between academic institutions and the startup ecosystem. The Director of IAV, Dr. E. Sreekumar, described the importance of participatory R&D and collaboration. The Innovation & Translation Facilitation Centre (ITFC) established by the institute plays a key role in supporting startups and industries, with a focus on combating infectious diseases. It also showcases KSUM’s commitment to fostering science-driven entrepreneurship in Kerala.?

QuantuMDx launches an advanced respiratory panel test for rapid diagnostics?

An important part of virology is the development of vaccines, which are essential public health tools capable of effectively reducing the impact of many viral illnesses. For instance, in May 2022, QuantuMDx Group Limited, an innovator in point-of-care diagnostics based in the UK, introduced its new respiratory test, the Q-POC? assay, designed to detect SARS-CoV-2, influenza viruses (types A and B), and RSV. This test is an advancement of the Q-POC? SARS-CoV-2 test that was released in 2021 and expands its multiplex capabilities, allowing for rapid testing in various healthcare environments.?

The Q-POC? assay uses the most recent sequence data for SARS-CoV-2, influenza A/B, and RSV, which guarantees thorough coverage of identified strains. It offers differential diagnoses and can enable quick triage in only a quarter of an hour at the point of care, which is especially beneficial for dependent patient populations. Early identification of co-infections can shorten treatment times, decrease hospital stays, and lower healthcare costs.?

Jonathan O’Halloran, the CEO of QuantuMDx, emphasized the importance of this launch for enhanced infectious disease diagnosis and management. This new assay indicates QuantuMDx's commitment to providing accessible and fast diagnostic solutions. Also, it shows the company's continuous efforts to broaden the Q-POC? test menu with innovative multiplexing solutions.?

Final thoughts?

Technological innovations in virology play an important role in advancing public health. New vaccines and rapid diagnostic tools enhance the ability to combat viral threats. In addition, collaboration between research institutions and startups promotes invention, improving responses to infectious diseases, and protecting global health for everyone.?

For more information on the latest developments in virology, feel free to contact our industry analyst here! You can also chat with them for any additional inquiries.?