AMR Future Brief| How Are Advances in Nutrigenomics Transforming Healthcare with Personalized Wellness?

Nutrigenomics is a scientific field that explores the relationship between nutrition, genes, and overall health. The term consists of two concepts, one is “nutritional” which pertains to the food individuals consume and the second one is “genomics” which relates to their unique genetic makeup or DNA. Traditional nutritional guidelines, like eating more whole grains and filling half the plate with fruits and vegetables, aim to help prevent major chronic diseases such as cancer, heart disease, and high blood pressure. However, people vary in their genetic makeup, which influences food preferences, nutrient utilization, and how food is metabolized. Nutritional genomics aims to understand how this interaction between diet and genes helps prevent diseases and promote better health at both individual and population levels.?

Genetic testing, AI, and epigenetics revolutionizing nutrigenomics?

This branch of scientific studies has undergone significant transformations over the last few years. These developments enable healthcare professionals and nutritionists to offer more personalized approaches toward diet and wellness. Recently, advances in genetic testing have made it easier to understand how individual genetic variations influence nutrient metabolism and health outcomes. Companies now offer direct-to-consumer genetic testing kits that analyze SNPs (Single Nucleotide Polymorphisms) to provide personalized dietary advice. These tests allow users to understand their predisposition to conditions such as lactose intolerance, gluten sensitivity, or how they metabolize fats and carbohydrates.?

On the other hand, AI and machine learning have been integrated into nutrigenomics research, enabling the development of platforms that have the potential for large datasets of genetic and nutritional information. AI algorithms help identify patterns in how specific nutrients interact with various genetic markers. These platforms offer more personalized and accurate dietary recommendations, considering the interactions between genes, environment, and lifestyle factors.?

A better understanding of diet that influences epigenetic changes is one of the latest breakthroughs in nutrigenomics. Epigenetics refers to the study of changes in gene expression that do not involve alterations to the DNA sequence itself. Research has shown that nutrients including folate, vitamin B12, and polyphenols can modify gene expression through epigenetic mechanisms such as DNA methylation. This has further opened new possibilities for preventive healthcare. For instance, pregnant women are now advised on how certain nutrients affect the gene expression of their unborn children, potentially reducing the risk of inherited diseases.??

The promising role of nutrigenomics in fitness and health?

Athletes and fitness enthusiasts are benefiting from nutrigenomics through personalized nutrition strategies aimed at enhancing performance and recovery. Genetic tests reveal how efficiently someone metabolizes macronutrients such as proteins and carbohydrates, their risk of inflammation, and how quickly they recover from exercise. Based on these insights, athletes are able to adjust their diets to improve muscle growth, endurance, and overall fitness outcomes. In professional sports, nutrigenomics helps coaches and nutritionists design diet plans that optimize performance while minimizing injury risks.?

The rise of personalized supplements, guided by nutrigenomic insights, is one of the latest applications of this field. Genetic testing identifies nutritional deficiencies or imbalances based on an individual’s unique genetic makeup. As a result, custom-tailored supplement plans are being developed to address specific needs, ensuring that people get the right balance of vitamins, minerals, and other nutrients. This approach is also being extended to functional foods and nutraceuticals, where products are designed to target genetic predispositions to certain health conditions, such as inflammation or oxidative stress.?

One of the most promising areas of nutrigenomics research is cancer prevention. Scientists have identified specific nutrients that help prevent certain types of cancer based on an individual’s genetic profile. For example, some people have genetic variants that make them more susceptible to colorectal cancer. Research has shown that increased intake of fiber, vitamin D, and antioxidants can help mitigate this risk. In oncology, nutrigenomics is being used to personalize dietary interventions for cancer patients, potentially improving treatment outcomes by supporting immune function and reducing side effects.?

LifeNome’s pioneering nutrigenomics program?

In April 2023, LifeNome, a precision health & wellness company announced the launch of its nutrigenomics program for registered dietitians and nutritionists. Ali Mostashari, the CEO of LifeNome, said that over the past few years, the company has created a precision consumer marketplace by utilizing individuals’ unique biometric, behavioral, and lifestyle data. This has led to the development of personalized products and services that advance individual health and well-being. With this launch, the company aims to expand its offerings in precision medicines by providing the most advanced nutrigenomic assessment technology on the market.?

Endnote?

Nutrigenomics has opened a new era of personalized healthcare by offering tailored health solutions. It helps healthcare professionals understand how genes influence nutrient metabolism and how nutrients affect gene expression. This enables them to provide individualized nutrition plans that promote optimal health and prevent diseases among individuals. With continuous technological advancements, this field is expected to unfold new possibilities in the coming years.??

To gain more insights into the emerging applications of nutrigenomics, contact our esteemed analysts today. For any further assistance, you can also chat with them here.?

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