AICAR is an inhibitor of PPARα transcription and a coactivator of PPARα.
AICAR/Acadesine.
AICAR is an inhibitor of PPARα transcription and a coactivator of PPARα.
AICAR is an adenosine analog that is phosphorylated in whole cells to form 5-aminoimidazole-4-carboxamide-1-D-ribofuranosyl-5′-monophosphate (ZMP), which stimulates AMPK activity. It works by accessing the nucleoside pool, significantly increasing adenosine levels during ATP breakdown.
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AICAR is also known as:
5-amino-1-β-D-ribofuranosyl-1H-imidazole-4-carboxamide, N1- (β-D-Ribofuranosyl) -5-aminoimidazole-4-carboxamide。
Acadesine (INN)
5-aminoimidazole-4-carboxamide-1-β-D-ribofuranoside
AICA-riboside
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