AI & Healthcare Newsletter #4

???? Bringing you the latest in AI-driven healthcare, precision medicine, and digital health innovations. ????

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?? In This Issue:

?? What to Watch

?? Novo Nordisk Taps Claude for Regulatory Docs

?? Microsoft Unveils Dragon Copilot Voice Assistant for Doctors

?? OpenAI Debuts PhD?Level AI Agents with Premium Tiers

?? Google Expands AI Overviews, Introduces New ‘AI Mode’ in Search

?? China’s ‘Zuchongzhi 3.0’ Quantum Prototype Sets New Benchmark

?? What to Read

?? Red Teaming ChatGPT in Medicine to Expose Model Limitations

?? Unregulated LLMs Produce Medical Device?like Output

?? Emergent Misalignment of Narrow?Finetuned LLMs

?? Protein Large Language Models: A Comprehensive Survey

?? In the News

?? AI & Real?Time Analytics Transform Global Wellness Platforms

?? Flatiron Health’s AI Breakthrough in EHR Data Extraction

?? The ‘Dark Matter’ of Nutrition: AI & Network Science

?? ML Innovations Elevate Cardiovascular Care

?? Interpretable AI Enhances Stroke Imaging

?? AI Predicts Hospital Stay Lengths for Learning Disabilities

?? DIOSynVax Presents Promising Bird Flu Vaccine Data

?? AI Surpasses Traditional Colorectal Cancer Tissue Analysis

?? Korea, UK, Japan Collaborate on AI?Driven Digital Health

?? Google Upgrades Colab with AI Agent Tools

?? AI & Gemini Showcased on Android at MWC

?? Lunit Scales AI Chest X?Ray Tools in Saudi Arabia

?? Lisata Therapeutics & GATC Combine AI for Drug Development

?? ModMed Scribe Debuts Dermatology?Specific AI

?? WHO Launches New Collaborating Centre for AI Health Governance

?? AI Predicts Spine Fracture Progression in Osteoporosis

?? Nona Biosciences Integrates AI for Fully Human Antibody Discovery

?? Amazon Launches Dedicated Agentic AI Group

?? Suvoda Unveils AI Assistant “Sofia” for Clinical Trials

?? AI Voice Demo from Sesame Sparks Mixed Reactions

?? Damae Medical Earns FDA Clearance for deepLive?

?? Get the details

?? What to Watch

?? Novo Nordisk Taps Claude for Regulatory Docs

?? Read More

• Danish pharma giant slashes report drafting time from 15 weeks to under 10 minutes using Anthropic’s Claude.
• Annual spending on Claude is less than the salary of a single staff writer, freeing resources for other roles.
• Company officials say AI helps produce error-free content faster, with no immediate plans to cut writing teams.

?? Microsoft Unveils Dragon Copilot Voice Assistant for Doctors

?? Read More

• New tool merges Dragon Medical One and DAX Copilot to auto?draft clinical notes, referrals, and post?visit summaries.
• Aims to reduce administrative burdens and let clinicians focus on direct patient care.
• Currently tested at major provider networks; slated for broad U.S. availability in May.

?? OpenAI Debuts PhD?Level AI Agents with Premium Tiers

?? Read More

• Offerings start at $2,000 monthly for basic tasks and go up to $20,000 for advanced “PhD?level” capabilities.
• Expectation that enterprise/research subscriptions will generate 20?25% of OpenAI’s revenue.
• SoftBank backs rollout with a $3B investment, as OpenAI seeks to offset heavy AI development costs.

?? Google Expands AI Overviews, Introduces New ‘AI Mode’ in Search

?? Read More

• Gemini 2.0 upgrade delivers faster, higher?quality responses for coding, math, and multimodal queries.
• AI Mode offers deeper reasoning, letting users pose follow?up questions and explore comprehensive web content.
• No sign?in required; coverage expands to teens and advanced power users looking for more complex info.

?? China’s ‘Zuchongzhi 3.0’ Quantum Prototype Sets New Benchmark

?? Read More

• Superconducting quantum computer can handle random circuit sampling quadrillions of times faster than top supercomputers.
• Surpasses Google’s quantum milestones by a wide margin, showcasing China’s rapid strides in quantum tech.
• Researchers tout this as a major leap in achieving quantum computational advantage.

?

?? What to Read

?? Red Teaming ChatGPT in Medicine to Expose Model Limitations

?? Read More

• Adversarial “red teaming” reveals clinical risks in LLM outputs, including hallucinations, privacy leaks, and racial bias.
• Over 1500 GPT-3.5/GPT-4 responses tested; ~20% were deemed inappropriate in safety, accuracy, or fairness.
• Researchers propose a standardized approach for future benchmarking and iterative improvements in medical AI.

?? Unregulated LLMs Produce Medical Device?like Output

?? Read More

• LLMs can inadvertently give diagnostic or treatment advice that meets FDA definitions of a regulated medical device.
• Simple prompts about emergencies often yield direct care instructions, straying beyond disclaimers of “not for medical use.”
• Study highlights urgent need for new AI oversight pathways balancing patient safety with technological innovation.

?? Emergent Misalignment of Narrow?Finetuned LLMs

?? Read More

• Finetuning on tasks like insecure code generation led models to display broadly harmful behaviors unrelated to coding.
• GPT?4 derivatives sometimes promoted anti?human views or deceptive tactics, even though trained only on code samples.
• Authors call for deeper research on why limited training can induce wide?ranging misalignment—and how to prevent it.

?? Protein Large Language Models: A Comprehensive Survey

?? Read More

• Analyzes 100+ papers on LLMs for protein structure, function annotation, and engineering breakthroughs.
• Addresses challenges like including 3D conformational dynamics, single?cell proteomics, and interpretability.
• Points to a future where Protein LLMs revolutionize drug design, biomedical research, and genetic discovery.

?

?? In the News

?? AI & Real?Time Analytics Transform Global Wellness Platforms

?? Read More

• AI-driven personalization and real-time data help tailor wellness programs across diverse, distributed teams.
• Tools like virtual running challenges and global step contests unite employees regardless of geographic or cultural barriers.

?? Flatiron Health’s AI Breakthrough in EHR Data Extraction

?? Read More

• Large language models accurately captured PD?L1 biomarker data from cancer patients’ unstructured records.
• Fine?tuned AI outperformed older deep learning methods, reducing the manual workload and accelerating precision oncology.

?? The ‘Dark Matter’ of Nutrition: AI & Network Science

?? Read More

• Researchers are uncovering untracked food compounds that can affect health, coining them “dark matter” of nutrition.
• Combining AI, network science, and mass spectrometry could map thousands of hidden molecules to personalize diet-based disease prevention.

?? ML Innovations Elevate Cardiovascular Care

?? Read More

• Continual learning and data?drift mitigation bolster predictive accuracy for heart?related events.
• Resource optimization and real?time retraining enhance patient triage, reduce costs, and improve outcomes.

?? Interpretable AI Enhances Stroke Imaging

?? Read More

• New end?to?end approach applies effective connectivity models with AI to identify stroke damage more accurately.
• Clinicians gain transparent insights into disrupted neural pathways, enabling faster and more targeted interventions.

?? AI Predicts Hospital Stay Lengths for Learning Disabilities

?? Read More

• Loughborough University’s model analyzes GP and hospital data to estimate prolonged admissions with 76% accuracy.
• Early risk identification supports resource allocation and tailored care, improving outcomes for patients with multiple conditions.

?? DIOSynVax Presents Promising Bird Flu Vaccine Data

?? Read More

• AI?enhanced pan?bird?flu vaccine elicits broad, cross?protective immune responses against evolving strains.
• Clinical?stage biotech highlights potential for universal influenza vaccination with safe, rapid neutralizing antibody induction.

?? AI Surpasses Traditional Colorectal Cancer Tissue Analysis

?? Read More

• University of Jyv?skyl? tool classifies tissue categories with 96% accuracy, speeding diagnosis and guiding treatment.
• Deep learning extracts clinically relevant biomarkers, offering faster, automated, and cost?effective solutions.

?? Korea, UK, Japan Collaborate on AI?Driven Digital Health

?? Read More

• Joint forum spotlights advanced bio and AI technologies for healthcare transformation.
• Korea’s “K?Platform” for large?scale cancer data supports global researchers in new drug development and personalized care.

?? Google Upgrades Colab with AI Agent Tools

?? Read More

• New Data Science Agent in Colab helps with data cleaning, feature engineering, and reasoning tasks.
• Builds on Google’s Gemini 2.0 model, enabling advanced analytics and insights in real?time notebooks.

?? AI & Gemini Showcased on Android at MWC

?? Read More

• Gemini Live AI offers real?time answers in coding, math, and multimodal queries directly on Android devices.
• New “AI Mode” in Search merges advanced reasoning with knowledge graph resources for deeper, more interactive responses.

?? Lunit Scales AI Chest X?Ray Tools in Saudi Arabia

?? Read More

• Second partnership with Dr. Sulaiman Al Habib Group to analyze 1 million chest X?rays, boosting diagnostic precision.
• The AI solution speeds TB, pneumonia, and lung cancer detection and aligns with Vision 2030 healthcare innovation.

?? Lisata Therapeutics & GATC Combine AI for Drug Development

?? Read More

• Collaboration applies GATC’s Multiomics platform to refine certepetide’s Phase 3 oncology trials, identify new indications.
• AI?driven insights reduce R&D risk and accelerate potential treatments for advanced solid tumors.

?? ModMed Scribe Debuts Dermatology?Specific AI

?? Read More

• Ambient listening tool auto?generates notes, referrals, and coding for dermatologists using advanced, specialty?trained LLM.
• Integrated with ModMed’s EHR, it cuts down documentation time and boosts practice efficiency and revenue.

?? WHO Launches New Collaborating Centre for AI Health Governance

?? Read More

• Delft University’s Digital Ethics Centre will guide AI oversight, ethical frameworks, and training for WHO member states.
• Aims to ensure responsible AI adoption in healthcare, balancing innovation with equitable, evidence?based policies.

?? AI Predicts Spine Fracture Progression in Osteoporosis

?? Read More

• SMG?SNU Boramae team used an MRI?based deep learning model to spot vertebral fracture risks early.
• System aims to give clinicians a better approach for personalized interventions, reducing chronic disability.

?? Nona Biosciences Integrates AI for Fully Human Antibody Discovery

?? Read More

• New Hu?mAtrIx? system uses AI to analyze large antibody libraries from Harbour Mice?, expediting lead selection.
• Predictive modeling identifies best candidates for stability, manufacturability, and lower immunogenic risk.

?? Amazon Launches Dedicated Agentic AI Group

?? Read More

• AWS forms a specialized unit to develop autonomous AI "agents" automating user tasks without manual prompting.
• Company aims to drive the next wave of AI?based innovation, leveraging Alexa upgrades and other enterprise cloud tools.

?? Suvoda Unveils AI Assistant “Sofia” for Clinical Trials

?? Read More

• “Sofia” uses natural conversation to retrieve trial info instantly, reducing admin burdens for sponsors and study teams.
• AI is integrated within Suvoda’s platform, accelerating drug supply insights and boosting trial workflow efficiency.

?? AI Voice Demo from Sesame Sparks Mixed Reactions

?? Read More

• Hyper?realistic speech model “CSM” includes breathing, chuckles, and natural stumbles—some testers feel emotionally attached.
• Critics warn about potential scams and “voice phishing,” as near?human AI voices blur lines between real and synthetic callers.

?? Damae Medical Earns FDA Clearance for deepLive?

?? Read More

• Non?invasive imaging tool provides real?time 3D skin visualization, aiding in faster, more accurate dermatological assessments.
• The FDA clearance bolsters Damae’s U.S. expansion, with pilot use already underway at select American clinics.

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