AdeG efflux pump as the main Tigecycline resistance in Acinetobacter baumannii
The tigecycline susceptibility of A. baumannii isolates was investigated in three medical centers in Iran.
The results of BMD susceptibility testing showed that >67.4% of isolates had MIC ≤4.
The MIC of tigecycline in the presence of EPI decreased in 38.7% of resistant isolates.
The results of semi-qPCR showed that the highest expression of efflux genes was related to adeG.