Active Motif Epigenetics Newsletter
Active Motif has teamed up with?EpiGenie?to deliver you the best collection of recent epigenetics news articles and educational resources to ensure that you can stay on top of what’s new in epigenetics research.
Two new sequencing methods may just make your day if you happen to be bidding for glorious insights into the epitranscriptome. Inspired by the bisulfite conversion used to assay DNA methylation, BID-seq and GLORI now enable single-nucleotide transcriptome-wide profiling of two crucial RNA modifications – N6-methyladenosine (m6A) and pseudouridine (the C5-glycoside isomer of uridine). Read More >>??
While microclimates shape environments along coastlines and urban jungles, this phenomenon isn’t restricted to macroscopic landscapes; now, a new study provides evidence that inflammatory signaling from the tumor microenvironment (TME) alters the epigenetic landscape by inducing the formation of a super-enhancer (SE) that drives tumorigenesis. Read More >>??
One of the longest-known and most studied epigenetic markers is DNA methylation, which can regulate gene expression and genomic organization in nearly all organisms. Here we take a look at some particularly interesting publications on both the epigenetic mechanisms and new methods being applied to this exciting field. Read More >>
Every avid trick-or-treater aspires to have the perfect Halloween costume; now, this recent study has revealed how an unwanted guest – SARS-CoV-2 – dons an epigenetic disguise to help this virus trick its way past host defenses to infect human cells! Read More >>
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Between the vast lands of DNA and proteins lies the ephemeral and dynamic world of chromatin-associated RNAs, a less-explored but utterly critical domain of the eukaryotic nucleus. Thankfully, RNA-focused researchers can now turn to a tagmentation-based profiling technique (“RT&Tag”) to map the landscape of regulatory chromatin-associated RNAs to aid this quest. Read More >>
Inflammaging is a somewhat new, but very engaging concept – how does our immune system affect the aging process? Here we look at research describing how accelerated epigenetic aging detected in the blood correlates with reduced kidney health as an example. These links may provide a means to further our understanding of inflammaging, and how to combat this chronic low-grade inflammatory process that may contribute to age-related disease development. Read More >>
In this episode of the Epigenetics Podcast, we caught up with Elena Gómez-Diaz from the Institute of Parasitology and Biomedicine López-Neyra at the Spanish National Research Council, who shared her work on Epigenetics in Human Malaria Parasites. Listen Now >>
In this episode of the Epigenetics Podcast, we caught up with Nick Pervolarakis from Active Motif to talk about bioinformatic analysis in epigenetics research. Listen Now >>
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2 年Great new monthly #newsletter for #epigenetics! Looking forward to reading it!